Promising combo for resistant breast cancer falls short – study halted

NCT ID NCT01589861

First seen Apr 25, 2026 · Last updated Jun 14, 2026 · Updated 7 times

Summary

This study tested a combination of two oral drugs, BKM120 and lapatinib, in 24 adults with HER2-positive breast cancer that had spread and no longer responded to trastuzumab. The goal was to find the safest dose and see if the combo could shrink tumors. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Institut Paoli-Calmettes

    Marseille, 13008, France

Conditions

Explore the condition pages connected to this study.