Georgetown University

This study tested a software platform called OR PathTrac that tracks how bacteria like Staphylococcus aureus spread during surgery. Researchers monitored 804 adult patients to see if giving feedback to surgical teams could reduce bacterial transmission and lower the risk of surgi…

This study tested a combination of two drugs, LEE011 and everolimus, in 12 people with advanced pancreatic cancer that had stopped responding to standard chemotherapy. The goal was to find the best dose and see if the combo could slow tumor growth. The approach aims to control th…

This study tested a low dose of nilotinib, a drug used for leukemia, in 37 people with mild to moderate Alzheimer's disease. The goal was to see if the drug is safe and can reach the brain to affect proteins linked to Alzheimer's, like tau and amyloid. Participants took the drug …

This study tested the safety and effects of nilotinib, a cancer drug, in 43 people with Dementia with Lewy Bodies (DLB). DLB is a common type of dementia that shares features with Parkinson's and Alzheimer's. The goal was to see if nilotinib is safe and changes brain biomarkers, …

This study tested whether a low dose of nilotinib, a drug already used for leukemia, is safe for people with Parkinson's disease. Researchers gave the drug or a placebo to 75 participants to check for side effects and measure changes in brain chemicals linked to Parkinson's. The …

This study tested a new combination of drugs (ABT-888 plus chemotherapy) in 64 people with pancreatic cancer that had spread. The goal was to see if adding ABT-888, which blocks cancer cells from fixing DNA damage, could make chemotherapy work better and shrink tumors. The study …

This study looked at whether a few phone calls with a trained peer coach could help young women (ages 21-30) who have a family history of BRCA gene mutations. The goal was to see if this support lowers cancer-related distress and helps them make informed choices about genetic cou…