Fudan University

This phase 3 trial compares two chemotherapy regimens for women with non-triple negative breast cancer after surgery. One group gets epirubicin plus cyclophosphamide followed by docetaxel (EC-T), the other gets paclitaxel plus carboplatin (PCb). The study includes 1560 participan…

This study looks at using the targeted drug osimertinib together with precise brain radiation in people with a specific type of lung cancer (EGFR-mutant) that has spread to the brain and causes symptoms. Researchers reviewed medical records from 300 patients across multiple hospi…

This study tests a new drug called cadonilimab combined with chemotherapy and radiation for people with stage III non-small cell lung cancer that cannot be removed by surgery. The goal is to see if this treatment can shrink tumors and keep the cancer under control. About 41 adult…

This study tests whether adding stereotactic radiotherapy (precise, high-dose radiation) to standard EGFR inhibitor drugs can improve outcomes for people with non-small cell lung cancer that has spread to the brain. About 202 participants whose brain tumors didn't fully shrink af…

This study tests a combination of the drug abemaciclib with standard chemotherapy (FOLFOX or FOLFIRI) in 16 adults with advanced colorectal cancer that has spread to the liver and hasn't responded to at least two prior treatments. The goal is to see if this combination can shrink…

This study tests whether a special low-calorie diet, called a fasting-mimicking diet, given before and after surgery can improve recovery and long-term outcomes for people with colorectal cancer. The diet is designed to be easier to follow than complete fasting, especially for ol…

This study compares 4 months versus 6 months of chemotherapy (capecitabine and oxaliplatin) in 1024 stomach cancer patients who had surgery. The goal is to see if the shorter treatment works just as well to prevent cancer from coming back, while causing fewer side effects. Partic…

This study tests a two-step treatment for people with early-stage MALT lymphoma, a slow-growing cancer of the lymph nodes. First, patients take a targeted drug called orelabrutinib. Then, based on how well the tumor responds, they receive an ultra-low dose of radiation (4Gy) to a…

This study tests a mix of chemotherapy, immunotherapy, and gut-friendly supplements for people with advanced esophageal cancer. The goal is to see if this approach can shrink tumors and keep them from growing back. About 50 participants will receive the treatment and be followed …

This study tests whether giving targeted drugs based on the genetic makeup of a person's advanced salivary gland cancer can shrink tumors or stop them from growing. About 88 adults with cancer that has spread or come back are enrolled. Researchers are checking how well these trea…

This study aimed to compare three different immunotherapy drug regimens given before and after surgery for people with early-stage non-small-cell lung cancer. The goal was to see which approach best prevented the cancer from coming back. However, the trial was withdrawn before en…

This study tests a combination of three drugs (bevacizumab, nab-paclitaxel, and platinum) as a second treatment for people with advanced non-squamous non-small cell lung cancer that does not have certain gene mutations. The participants' cancer had already gotten worse after firs…

This study looks at whether testing stool (feces) for certain DNA changes and bacteria genes can help find stomach cancer early. Researchers will follow 3000 people, including those with and without cancer, to see how well the test works. The goal is to improve early diagnosis an…

This study looks at whether artificial intelligence can accurately determine the depth of early esophageal cancer from endoscopic images. Researchers will review past records and images from 890 patients who had their tumors removed. The goal is to see if AI can help doctors deci…

This study tests a nurse-led program that starts at least a week before liver cancer surgery. It includes exercise, nutrition advice, mental support, and help quitting smoking or drinking. The goal is to see if this program helps patients stay stronger, feel less anxious, and hav…

This study looks at whether drinking cola can help relieve sudden food blockages in the esophagus for people with esophageal cancer. About 50 participants will be randomly assigned to drink cola or receive standard care. The main goal is to see if cola improves the chance of clea…

This study is testing whether tiny particles called exosomes, found in blood and lung fluid, can predict how well treatment works in people with advanced non-small cell lung cancer. Researchers will collect samples from 100 patients before and during standard therapy. The goal is…

This study, run by Fudan University and local health authorities, uses computer models to predict the best way to use dengue vaccines in Yunnan, China. Researchers will collect blood samples from 220 residents to measure antibody levels and simulate different vaccination scenario…

This study looks at whether PET-CT scans can predict if non-small cell lung cancer has spread to nearby lymph nodes. Researchers will compare scan results with actual tissue samples from surgery in 280 patients. The goal is to improve how doctors plan treatment without needing ex…

This study looks at how anemia changes blood flow in the smallest blood vessels (microcirculation) in patients having open surgery for gastric cancer. Researchers will compare 27 anemic patients with 27 non-anemic patients, all receiving standard goal-directed fluid therapy. They…

This study was designed to see if adding chemotherapy to radiation therapy after incomplete surgery for thymoma or thymic carcinoma could improve survival. It planned to enroll adults aged 18-75 who had incomplete tumor removal. However, the trial was withdrawn before any partici…

This study looked at 197 breast cancer patients whose cancer had spread. It compared those whose tumors changed from hormone-sensitive (ER-positive) to hormone-insensitive (ER-negative) with those who had triple-negative breast cancer from the start. Using a special PET scan, res…