Ciusss De L'est De L'île De Montréal

This study tests a higher dose of UM171, a molecule that helps grow cord blood stem cells in the lab, for adults with high-risk blood cancers like leukemia who cannot find a suitable donor. The goal is to see if this approach makes the transplant less toxic and helps patients rec…

This study tests a modified, shorter chemotherapy schedule given directly into the abdomen after surgery for cancers that have spread to the lining of the belly. The goal is to see if this two-day treatment is easier to complete than the standard five-day version. About 25 adults…

This study tests whether melatonin, a natural sleep hormone, can help treat delirium (sudden confusion) in intensive care unit patients. Researchers want to see if it's possible to run a larger trial and if melatonin can shorten the time patients spend in a confused state. The st…

This study tests whether a safe, non-invasive brain stimulation technique called tDCS can reduce depressive symptoms in people with borderline personality disorder (BPD). Sixty adults with BPD and moderate-to-severe depression will receive either real or fake tDCS sessions at hom…

This study aims to find the best dose of pain medicine given through an epidural after open abdominal surgery. About 60 adults having a large belly incision will receive different doses to see which works best for pain control on the first day after surgery. The goal is to improv…

This study looks at a common but often overlooked side effect of stem cell transplants in women: chronic graft-versus-host disease (cGVHD) in the genital area. Researchers will track 100 women over 2-3 years to learn how often it happens, what symptoms appear, and how treatments …

This study looks at 110 adults having surgery to see if brain wave patterns and thinking tests can predict how much propofol (a sleep medicine) is needed for deep anesthesia. Researchers will measure brain activity before and during anesthesia. The goal is to understand why peopl…

This study follows 200 adults with advanced chronic kidney disease as they start dialysis at home or in a center. Researchers will track changes in quality of life, frailty, fatigue, and mood every 3 months for a year. The goal is to see if home dialysis helps patients stay healt…