Charite University, Berlin, Germany

This study tests a new treatment called CAR-T cell therapy against a standard drug, rituximab, in people with active rheumatoid arthritis that hasn't improved with other treatments. The goal is to see if CAR-T cells are safe and can reduce harmful antibodies linked to the disease…

This study tests whether a digital decision-support tool can help doctors better follow guidelines to prevent postoperative delirium (sudden confusion) in older adults after surgery. The study includes 845 patients aged 70 and older having elective surgery. The tool aims to impro…

This study compares standard cognitive behavioral therapy (CBT) to CBT plus a group training called Kiesler Circle Training (KCT) that focuses on improving interpersonal skills. 156 adults with depression or anxiety and above-average social difficulties are participating. The goa…

This study tests whether vericiguat, a drug already used for heart failure, can improve physical function and reduce fatigue in people with post-COVID syndrome. About 104 adults aged 18-50 will take either vericiguat or a placebo for 10 weeks. The goal is to see if the drug helps…

This study brings together 60 doctors and naturopaths from clinics that have used long-term fasting (4+ days with very few calories) for years. They will share their experiences and agree on scientific guidelines for safe and effective medical fasting. The goal is to create a wor…

This study aims to find out what factors can predict changes in thinking and memory after deep brain stimulation (DBS) for Parkinson's disease. Researchers will test 30 patients before and up to 5 years after surgery using brain scans, thinking tests, and other measures. The goal…

This study tests a special body suit that uses mild electric pulses to stimulate muscles during exercise on the International Space Station. Eight astronauts will wear the suit during their workouts to see if it helps prevent muscle loss and stiffness in microgravity. Researchers…

This study looks at over 900,000 hospital patient records to find out which medications might make older adults more likely to fall. Researchers are checking a German list of risky drugs (PRISCUS) and looking for other medicines that could be added. The goal is to help doctors pr…