Centre Leon Berard

This study is testing whether giving an immunotherapy drug called pembrolizumab before surgery can help people with certain localized, operable cancers. The goal is to see if this pre-surgery treatment can shrink or even eliminate the tumor, potentially leading to better long-ter…

This study is testing if starting with a stronger drug (ponatinib) for 6 months, then switching to a standard drug (imatinib), can help people with a type of blood cancer called CML. The goal is to get the cancer under such good control that some patients might eventually be able…

This study is testing a new combination of two drugs, HDM201 and pazopanib, for people with advanced soft tissue sarcoma that has spread and stopped responding to standard chemotherapy. The first part aims to find the safest dose of the combination. The second part will gather ea…

This study is testing if adding a drug called atezolizumab (an immunotherapy) to the standard treatment of radiotherapy and surgery works better for soft tissue sarcoma. It will involve 62 adults with a type of sarcoma that can be removed by surgery. The main goal is to see if th…

This study is testing whether adding a medication called pegfilgrastim to standard pre-surgery treatment improves outcomes for people with HER2-positive breast cancer. Pegfilgrastim helps boost white blood cell counts. Researchers want to see if this boost helps the main cancer d…

This early-stage study is testing a focused ultrasound technique (HIFU) to destroy pancreatic tumors that cannot be removed by surgery. It is for patients whose cancer has not progressed after initial chemotherapy. The main goals are to see if the procedure is safe and if it help…

This study is testing if adding an experimental drug called NP137 to standard immunotherapy helps patients with advanced solid tumors. It focuses on people whose cancer has stopped responding well to their current immunotherapy. The goal is to see if the combination can better co…

This study compares two approaches for cancer patients who visit emergency rooms with urgent needs. It tests whether systematically referring patients to a palliative care team (comfort care focused on quality of life) leads to less aggressive medical treatments near the end of l…

This study aims to understand and track the long-term health problems that can develop in cancer survivors after their initial treatment is successful. It follows 500 adults who have finished treatment for certain cancers (like breast cancer, lymphoma, and leukemia) and are in re…