Centre Hospitalier De L'université De Montréal (chum)

This study tests whether giving a laser treatment (transscleral cyclophotocoagulation) to lower eye pressure before a Boston keratoprosthesis (a plastic cornea implant) can prevent or slow glaucoma. Twenty adults who need the implant will receive one of two laser types 4-8 weeks …

This study tests whether treating a donor cornea with a special light and vitamin B2 (riboflavin) before using it as a support for the Boston artificial cornea can prevent the graft from melting. About 40 people who need this artificial cornea will be split into two groups: one g…

This study tests a portable device that uses electrical signals to detect early fluid buildup in the lungs of heart failure patients. The goal is to see if the device works as well as standard imaging methods like ultrasound. If successful, it could help patients manage their con…

This study tests a new way to find air leaks in the lungs during surgery. Doctors will pump a harmless glycerine smoke into the lungs and watch for it to escape through leaks using a standard camera. The goal is to see if this smoke method works better than the usual water test, …

This early-stage study tests a drug called KAN-004 in 21 adults who have diarrhea or colon inflammation from cancer immunotherapy. The main goal is to see if the drug is safe and tolerable. Participants must have a solid tumor and be able to swallow capsules.

This study aims to find out how many new mothers at a high-risk pregnancy clinic experience postpartum depression. Researchers will screen 100 women using a simple questionnaire and track how often the condition is detected. The goal is to improve screening and ensure women get t…

This study checks the safety of a radioactive substance called N-13 ammonia, used in heart PET scans to see if arteries are blocked. About 20,000 adults who need a heart PET scan will receive this tracer, and researchers will watch for any side effects. The goal is to make sure t…

This study aims to understand how 350 regular cannabis users aged 18-24 consume the drug in their everyday lives over two years. Participants will use a mobile app to report daily details like product type, dosage, and source. The goal is to identify patterns and changes in use o…

This study collects and analyzes tears from 300 people with healthy eyes or with conditions like dry eye, eye infections, allergic conjunctivitis, or mucous membrane pemphigoid. The goal is to create a unique protein and metabolite "fingerprint" for each disease to better underst…

This study is testing whether a special PET scan using F-choline can help doctors see and manage a variety of cancers and other medical conditions. Researchers will enroll 500 adults with known or suspected conditions where this scan might provide useful information. The goal is …

This study aims to improve how doctors predict prostate cancer progression and treatment response by combining advanced PSMA-PET scans with artificial intelligence. Researchers will collect scan data from 1,000 men with prostate cancer and use deep learning to discover imaging bi…

This study looks at whether a diet low in methionine (an amino acid) can change the bacteria in your gut and lower inflammation. Forty healthy adults will follow the diet for several weeks, with some also taking methionine supplements or a placebo. Researchers will measure gut ba…