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15,000 patients to reveal hidden heart dangers of Same-Day surgery

NCT ID NCT04973397

Knowledge-focused Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 15,000 adults aged 45+ (or 65+ without risk factors) who are having same-day noncardiac surgery. The goal is to learn how often heart problems and other complications happen after these surgeries, and to create tools that help doctors predict and reduce risks. Participants will be monitored for unplanned hospital visits or admissions after their procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 15,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2021

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All eligible adults undergoing elective same-day noncardiac surgery

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 45-64 years of age with at least one risk factor, or ≥65 years of age; * undergoing elective noncardiac same-day surgery; * planned duration in the operating room 60 minutes or more; * provided written consent. Exclusion Criteria: * intervention does not require the presence of an anesthesiologist; * procedure is performed by a nonsurgical specialty (e.g., gastroenterology, pneumology, radio-oncology or radiology); * intervention is an ophthalmologic procedure; * previously enrolled in the VALIANCE study.

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Conditions

The condition(s) this trial relates to.

myocardial infarction Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myocardial infarction Preoperative care Surgery--complications

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    14 sites in 4 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire de Sherbrooke

    ACTIVE_NOT_RECRUITING

    Sherbrooke, Quebec, Canada

  • Centre Hospitalier de l'Université de Montréal (CHUM)

    RECRUITING

    Montreal, Quebec, H2X0C1, Canada

  • Cleveland Clinic Foundation Fairview Campus

    RECRUITING

    Cleveland, Ohio, 44111, United States

  • Cleveland Clinic Foundation Main Campus

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Hamilton General Hospital

    RECRUITING

    Hamilton, Ontario, Canada

  • Hospital Clinic Barcelona

    RECRUITING

    Barcelona, Spain

  • Juravinski Hospital and Cancer Centre

    RECRUITING

    Hamilton, Ontario, Canada

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Maasstad Ziekenhuis Rotterdam

    RECRUITING

    Rotterdam, Netherlands

  • McMaster University Medical Centre

    RECRUITING

    Hamilton, Ontario, Canada

  • Memorial Hermann Texas Medical Center UT Health

    RECRUITING

    Houston, Texas, 77030, United States

  • Mount Sinai Hospital

    RECRUITING

    Toronto, Ontario, M5G 1X5, Canada

  • St-Joseph's Healthcare Hamilton

    ACTIVE_NOT_RECRUITING

    Hamilton, Ontario, L8N 4A6, Canada

  • St-Micheal's Hospital

    RECRUITING

    Toronto, Ontario, Canada

  • Toronto Western Hospital

    RECRUITING

    Toronto, Ontario, M5T 2S8, Canada

  • Wake Forest Baptist Medical Centre

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.