New ultrasound technique could spot hidden liver cancers
NCT ID NCT06345508
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a new type of ultrasound, called quantitative ultrasound (QUS), can find liver cancers that standard ultrasound often misses. About 328 adults at risk for liver cancer will receive both QUS and standard ultrasound, and results will be compared to MRI or biopsy. If QUS works better, it could help catch liver cancer earlier, when it is more treatable.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Quantitative Ultrasound (QUS)
- What this could lead to
- If successful, this could make liver cancer detection more accurate and accessible, catching tumors early when they are curable.
- What could go wrong
- This is a diagnostic study, not a treatment. The new technique may not prove significantly better than standard ultrasound, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 328 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2024
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients scheduled for US- or MRI-based surveillance of HCC or undergoing MRI-based imaging for characterization of liver nodules as part of their clinical standard of care.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Adult patients scheduled for US- or MRI-based surveillance of HCC or undergoing MRI-based imaging for characterization of liver nodules as part of their clinical standard of care. Exclusion Criteria: \- Patients with prior locoregional or systemic therapy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre Hospitalier de l'Université de Montréal (CHUM)
RECRUITINGMontreal, Quebec, H2X 0A9, Canada
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