Cancer Institute And Hospital, Chinese Academy Of Medical Sciences

This study tests whether adding the immunotherapy drug toripalimab to standard chemotherapy and radiation can help people with large, hard-to-treat lung cancer. About 50 adults with advanced non-small cell lung cancer that cannot be removed by surgery will receive the combination…

This study tests a combination of the drug glofitamab with chemotherapy (GemOx) in 40 adults with a type of lymphoma that did not respond to initial treatment. The main goal is to see how many patients have their tumors completely disappear for at least 4 weeks. Participants must…

This study tests a three-drug combination (selinexor, thalidomide, and dexamethasone) in 40 adults with a rare blood disorder called Langerhans cell histiocytosis (LCH) that has not responded to or has returned after prior treatment. The goal is to see if the regimen can control …

This study looks at whether giving extra radiation to the internal mammary lymph nodes can help prevent breast cancer from coming back in high-risk patients. About 2,400 people who had a mastectomy or breast-conserving surgery with positive lymph nodes are taking part. The goal i…

This study tests whether adding the drug toripalimab to standard chemoradiation can help people with high-risk, locally advanced cervical cancer live longer without the cancer getting worse. The trial involves 57 participants who have not had prior treatment. After the initial tr…

This study tests a combination of three drugs (orelabrutinib, zuberitamab, and chemotherapy) in 65 adults with untreated marginal zone lymphoma, a slow-growing blood cancer. The goal is to see if the treatment can make all signs of cancer disappear and keep it away for at least 2…

This study tests a shorter, more intense radiation schedule (hypofractionation) for people with thymic tumors who have had the tumor completely removed. The goal is to see if this approach can prevent the tumor from returning while keeping side effects low. About 50 adults with s…

This study tests a shorter, more targeted radiation therapy (accelerated partial breast irradiation) given after breast-conserving surgery in people with early-stage breast cancer. The goal is to see if this approach controls cancer recurrence and reduces side effects compared to…

This study enrolls 4,000 people with urothelial carcinoma (bladder cancer) to test whether artificial intelligence can accurately predict HER2 protein levels using MRI scans and tissue images. The goal is to guide targeted therapy decisions without needing invasive biopsies. Rese…

This study reviews medical records from 300 people with advanced stomach or gastroesophageal junction cancer. Researchers want to see how different combinations of chemotherapy, radiation, or other treatments given before and after surgery affect how long patients live and whethe…

This study involves 10,000 people with non-small cell lung cancer who received immunotherapy before surgery. Researchers want to find out which follow-up treatments work best to improve survival and prevent cancer from coming back. By analyzing real-world data, they hope to ident…

This study looks at whether changes in tumor DNA found in the blood can help predict how B-cell non-Hodgkin lymphoma will progress. Researchers will collect blood samples from 60 patients before and during treatment to see if DNA levels relate to survival or response. This is an …

This study follows 138 people who had surgery for esophageal cancer to see how often they experience reflux afterward. Researchers use a simple test called PEPTEST to measure stomach acid in saliva before surgery, at discharge, and 1, 3, and 6 months later. The goal is to find pa…