Biogen

This study tested a new oral drug, BIIB091, for people with relapsing forms of multiple sclerosis (MS). In the first part, 127 participants took either BIIB091 or an approved MS drug (diroximel fumarate) to check safety. The goal was to see if BIIB091, alone or combined with the …

This study tested the safety and how the body processes the drug diroximel fumarate in adults with relapsing forms of multiple sclerosis (MS) from the Asia-Pacific region. It involved 136 participants who took the drug for either 24 or 48 weeks. The main goal was to see how well …

This study looked at whether adding a drug called nusinersen could help young children with spinal muscular atrophy (SMA) who were still having movement problems even after receiving a one-time gene therapy. Researchers enrolled 46 children under age 3 to receive nusinersen injec…

This study tested a drug called omaveloxolone (RTA 408) to see if it could help people with Friedreich's ataxia, a rare genetic disease that affects movement and coordination. Researchers enrolled 172 participants to measure the drug's safety and its effects on physical effort an…

This study tested whether regular spinal fluid injections of an experimental drug called nusinersen could prevent or delay the onset of spinal muscular atrophy (SMA) in infants who had the genetic cause but showed no symptoms yet. It involved 25 infants under 6 weeks old who rece…

This study aimed to understand if a drug approved for Friedrich's Ataxia (omaveloxolone) changes how the body processes a common heartburn medicine called omeprazole. Researchers enrolled 22 healthy volunteers who took both drugs over a 17-day stay in a research center. The main …

This study tested whether three different injection devices deliver the same amount of litifilimab into the bloodstream. Researchers compared a standard syringe against an auto-injector pen and a wearable on-body injector in 404 healthy volunteers. The goal was to see if the newe…

This study aimed to see if a drug for Friedreich's Ataxia (FA) works the same way in the body when sprinkled on low-fat yogurt as it does when taken as a whole capsule. It involved 52 healthy adults who tried both methods. The goal was to learn if yogurt could be another simple o…

This early-stage study aimed to see if a new drug called BIIB800 behaves similarly in the body to an existing drug, Actemra. It involved 300 healthy male volunteers who received a single injection of one of the drugs. Researchers measured drug levels in the blood, safety, and the…

This early-stage study aimed to understand how an experimental Alzheimer's drug, BIIB080, travels through the brain and spinal cord. Researchers gave a tiny, traceable dose of the drug to 5 healthy adults and used special brain scans to see where it went. The main goals were to m…