Biogen

This study tested a drug called nusinersen in 25 babies who have the genetic markers for spinal muscular atrophy (SMA) but no symptoms yet. The goal was to see if early treatment could delay or prevent the need for breathing help or death. The drug is given via a spinal injection…

This study tested a drug called diroximel fumarate in 136 adults from East Asia with relapsing multiple sclerosis (MS). The goal was to see if the drug is safe and tolerable over 24 to 48 weeks. Researchers monitored side effects, lab results, and how the drug moves through the b…

This study tested a new drug called BIIB091, taken alone or with an existing MS drug (diroximel fumarate), in 127 people with relapsing forms of multiple sclerosis. The goal was to check safety and see if the combination reduces new brain inflammation spots better than the existi…

This study tested a drug called RTA 408 (omaveloxolone) in 172 people with Friedreich's ataxia, a rare genetic disease that affects movement and coordination. The goal was to see if the drug is safe and can improve exercise ability and daily function. Participants took the drug o…

This study looked at whether adding a medicine called nusinersen can help children under 3 with spinal muscular atrophy (SMA) who still have muscle problems even after receiving gene therapy. The 46 children received several doses of nusinersen over about 2 years. Researchers che…

This study looked at whether a tablet form of the drug omaveloxolone (used for Friedreich's Ataxia) that dissolves in liquid is processed by the body the same way as the current capsule form. 70 healthy adults each took both forms, with a 14-day break in between. The goal was to …

This study looked at how a drug being tested for Alzheimer's disease (BIIB080) spreads through the brain and spinal cord. Five healthy adults received a tiny radioactive version of the drug along with a regular dose. Researchers used PET scans to track where the drug went and che…

This study tested whether a new drug called BIIB800 works similarly to an approved drug, Actemra, in the body. It involved 300 healthy male volunteers who received a single injection. The goal was to measure how the drugs are absorbed and processed, not to treat any disease.

This study looked at how the drug omaveloxolone (used for Friedreich's Ataxia) affects the way the body processes omeprazole (a common heartburn medicine). Twenty-two healthy adults took both drugs in a set order, and researchers measured drug levels in their blood. The goal was …

This study looked at how the body processes the drug omaveloxolone (SKYCLARYS®) when taken as a whole capsule versus when the capsule contents are sprinkled over low-fat, non-Greek yogurt. 52 healthy adults each took the drug both ways, with a 14-day break in between. The goal wa…

This study tested three different devices (a pre-filled syringe, an autoinjector, and an on-body injector) to give the drug litifilimab under the skin. The goal was to see how the body processes the drug with each device. 404 healthy volunteers took part, and the study focused on…