Bayer

This study follows men in India with metastatic hormone-sensitive prostate cancer who are already receiving darolutamide plus androgen deprivation therapy as part of their routine care. Researchers will track side effects, treatment changes, and lab results over up to one year. T…

This early-stage study tests whether it is safe to take nitroglycerin spray (used for chest pain) together with an experimental drug called nurandociguat (designed to help kidneys) in 36 adults with stable coronary artery disease. Both drugs widen blood vessels, so the main conce…

This study tests a single injection of AB-1005 gene therapy directly into the brain for Japanese adults with moderate Parkinson's disease. The goal is to see if it is safe and can improve daily movement. Eight participants will be followed for 18 months.

This observational study will follow 40 children aged 7 to 12 with hemophilia A who are already prescribed damoctocog alfa pegol (Jivi) to prevent bleeding. Researchers will collect data from routine care, including bleeding episodes and treatment patterns, over two years. The go…

This study looks at the safety and effectiveness of Octocog alfa, a lab-made clotting factor, when used to treat sudden bleeding episodes in adults with severe hemophilia A. About 33 people in India who have used factor VIII before will take part. Researchers will track side effe…

This study follows 1,500 women in the U.S. who are starting elinzanetant, a new hormone-free medicine for hot flashes and night sweats during menopause. Researchers will track how well it works, how safe it is, and how it affects sleep and quality of life using phone surveys and …

This study looks at women aged 40 and older who still have a uterus and have started estrogen therapy for menopause symptoms or bone loss. Estrogen alone can thicken the womb lining, raising the risk of precancerous changes and cancer, so a progestogen is usually added for protec…

This study looks at whether a digital tool called Luscii is practical and acceptable for people with a rare heart condition called ATTR-CM. About 60 adults in Austria, Germany, and Italy will use a smartphone app and home devices to share health information with their care team. …

This Phase 1 study in healthy adults aims to find out whether sevabertinib, an experimental cancer drug, changes how the body processes metformin, a common diabetes medication. Researchers suspect sevabertinib might block kidney transporters that help remove metformin from the bo…

This observational study will collect data from health records of 850 children under 2 years old who have venous thromboembolism (blood clots). The goal is to see how doctors prescribe rivaroxaban (Xarelto) and other standard blood thinners, and to track any serious bleeding. No …

This study follows 50 pregnant women with Chagas disease who take or have taken nifurtimox, to see if the drug causes harm to the baby or mother. Researchers will track birth defects, pregnancy outcomes, and infant health up to 12 months old. The goal is to collect safety data, n…