Allegheny Singer Research Institute (also Known As Allegheny Health Network Research Institute)

This early-phase study tests a new treatment for people whose cancer has spread to the lining of the lungs (pleura) or who have mesothelioma. Doctors collect fluid from around the lungs, grow the patient's own immune cells in a lab, and then put them back into the chest along wit…

This early study tests whether deep brain stimulation (DBS) can help people with severe opioid addiction who keep relapsing despite standard treatments. Only 3 participants will receive DBS to a brain region linked to reward and craving. The goal is to see if it is safe and can r…

This study looks at how different group exercise programs affect fitness and muscle strength in women who have finished breast cancer treatment. About 15 women will try one of four supervised resistance training routines. The goal is to see which approach best improves heart heal…

This study tests whether tamsulosin, a drug typically used for men with prostate problems, can shorten the time women need a catheter after pelvic reconstructive surgery. About 154 women who have trouble emptying their bladder after surgery will receive either tamsulosin or a pla…

This study tests whether a program of resistance training (like lifting weights) plus a high-protein drink after workouts can help women with breast cancer maintain muscle and reduce fat while they undergo chemotherapy. About 30 women will be randomly assigned to start the progra…

This study compares three standard pain management methods used during minimally invasive cancer surgery. 48 adults having surgery for cancers of the liver, stomach, pancreas, or other organs will be randomly assigned to one of three groups. The goal is to see which method provid…

This study looks at two different exercise programs to see which one helps women gain muscle mass after finishing breast cancer treatment. Researchers will track changes in muscle and fat, as well as how well participants stick with the program. The goal is to find the best way t…

This study looks at how well the bones in the neck fuse together after surgery using two different materials: a new titanium device (Tritanium C) or a bone graft from a donor. Researchers will track 60 adults aged 18-80 with degenerative disc disease who need surgery on one or tw…