Prostate drug tested on women for bladder relief after surgery
NCT ID NCT04597372
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether tamsulosin, a drug often used for men with prostate problems, can shorten the time women need a catheter after pelvic reconstructive surgery. About 154 women who have trouble emptying their bladder after surgery will receive either tamsulosin or a placebo. The goal is to see if the drug helps them regain normal urination faster and reduces infections.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 154 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 years or older * willing and able to provide informed consent * postoperative urinary retention as defined by a failed RGVT prior to hospital discharge * Ability to speak and read English * Tolerate pill ingestion Exclusion Criteria: * allergy/intolerance to Tamsulosin or sulfa drugs * preoperative history of urinary retention as defined by preoperative post void residual of \>150mL * current use of alpha antagonist medication for hypertension * severe dementia * end stage renal or liver disease * history of severe heart failure or major cardiovascular event in the last 6 months
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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West Penn Hospital
RECRUITINGPittsburgh, Pennsylvania, 15224, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New bladder training cuts Post-Surgery catheter woes
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- Knee surgery painkiller linked to catheter need – new trial seeks safer option