Ventilator-associated pneumonia (VAP)
Clinical trials for Ventilator-associated pneumonia (VAP) explained in plain language.
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Can tailored antibiotic doses beat resistance in the sickest patients?
Disease control Not yet recruitingCritically ill patients on breathing machines often get hospital-acquired lung infections. This trial tests whether adjusting antibiotic doses using drug level monitoring and software works better than standard dosing. About 610 adults in intensive care units will receive either …
Matched conditions: VENTILATOR-ASSOCIATED PNEUMONIA (VAP)
Sponsor: The University of Queensland • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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New test aims to get the right antibiotics to ICU pneumonia patients faster
Disease control Not yet recruitingThis study tests whether a rapid test (multiplex PCR) combined with a treatment algorithm can help doctors choose the best antibiotics sooner for patients on ventilators who develop pneumonia. About 124 adults in intensive care will be randomly assigned to either the new strategy…
Matched conditions: VENTILATOR-ASSOCIATED PNEUMONIA (VAP)
Phase 4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New blood test may spot deadly pneumonia in ventilator patients earlier
Diagnosis Not yet recruitingThis study will enroll 80 adults on ventilators for at least 48 hours who develop pneumonia. Researchers will measure a protein called heparin-binding protein (HBP) in the blood and compare it to standard platelet tests to see which better predicts survival and recovery. The goal…
Matched conditions: VENTILATOR-ASSOCIATED PNEUMONIA (VAP)
Sponsor: Esraa Hamdy Thabit Riad • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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Can better nurse training reduce ICU complications?
Knowledge-focused Not yet recruitingThis trial tests whether a structured training program for ICU nurses, focusing on respiratory and renal care with case-based discussions, improves their clinical reasoning, knowledge, and collaboration with doctors. The study involves 140 participants, including nurses and mecha…
Matched conditions: VENTILATOR-ASSOCIATED PNEUMONIA (VAP)
Sponsor: Hiroshima University • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Nurse training aims to cut ICU infections in developing nations
Knowledge-focused Not yet recruitingThis study tests whether training nurses to follow evidence-based guidelines can reduce infections and other complications in intensive care units (ICUs) in low- and middle-income countries. About 50 nurses will be trained and their patients' outcomes compared to usual care. The …
Matched conditions: VENTILATOR-ASSOCIATED PNEUMONIA (VAP)
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC