VENOUS THROMBOEMBOLISM (VTE)

This study tests whether a combination of two blood thinners (rivaroxaban and aspirin) can prevent heart attacks, strokes, and blood clots in people who had hip fracture surgery and also suffered a heart injury. About 100 adults aged 45 and older will receive either the drug comb…

This study tests whether adding colchicine, an anti-inflammatory medicine, to standard blood thinners can reduce the risk of long-term vein damage (post-thrombotic syndrome) in people with a first-time deep vein clot in the leg. About 940 adults will receive either colchicine or …

This study will compare two common treatments—aspirin tablets and heparin injections—to see which is better at preventing dangerous blood clots in people who break their hip. Over 21,000 patients aged 60 and older from 96 UK hospitals will take part. Hospitals will switch between…

This study tests an experimental drug, REGN7508, to see if it works better than the standard blood thinner apixaban for treating and preventing blood clots in people with cancer. About 1,600 participants with or without cancer will be enrolled. The goal is to check how safe and e…

This study will test a new, non-invasive bedside imaging technique called 3D electrical impedance tomography (3D-EIT) to see if it can accurately diagnose and monitor pulmonary embolism (blood clots in the lungs). About 115 adults with and without clots will be scanned, and the r…

This study tests whether a blood thinner called enoxaparin can prevent dangerous blood clots in critically ill teenagers. About 802 teens aged 12-18 in intensive care with a central line and infection will be enrolled. The goal is to see if the drug safely reduces clot risk witho…

This study tests whether watching a short educational video before receiving a blood thinner injection (LMWH) after childbirth can reduce anxiety and pain. About 160 new mothers will either get the usual explanation or also watch the video. The goal is to see if the video helps t…

This study will see if using virtual care technologies in hospital units can reduce problems like falls, infections, and readmissions while improving patient satisfaction. About 10,000 adults admitted to six hospital units at Duke University Hospital will take part. Three units w…