New scanner could spot dangerous lung clots without radiation
NCT ID NCT07560293
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test a new, non-invasive bedside scan (3D-EIT) to see if it can accurately diagnose and monitor pulmonary embolism (blood clots in the lungs) without using radiation. About 115 adults with and without clots will participate. The goal is to provide a safer, easier way to detect and track this serious condition.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 115 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants will be recruited from Beijing Tsinghua Changgung Hospital. The study population will include: (1) adult patients with a first episode of pulmonary embolism confirmed by CT pulmonary angiography, and (2) control participants without pulmonary embolism or deep vein thrombosis who are scheduled for saphenous vein radiofrequency ablation for varicose veins. Control participants will undergo screening to exclude venous thromboembolism before enrollment.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Body mass index (BMI) less than 50 kg/m² * Able to provide written informed consent * first episode of pulmonary embolism confirmed by CT pulmonary angiography (CTPA), with or without CT venography (CTV) Exclusion Criteria: * Previous diagnosis of pulmonary embolism * Pregnancy * Thoracic deformity or chest wall abnormality preventing proper placement of the EIT electrode belt * Contraindications to EIT use, including implantable cardioverter-defibrillator, pacemaker, implanted pumps, or chest wounds limiting electrode placement * Concurrent participation in another interventional clinical study Hemodynamic instability requiring emergency intervention that precludes completion of the EIT examination (PE cohort only) * Any other condition judged by the investigator to make the participant unsuitable for study participation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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