UVEAL MELANOMA
Clinical trials for UVEAL MELANOMA explained in plain language.
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Experimental vaccine aims to stop rare eye cancer from returning
⭐️ VACCINE ⭐️ CompletedThis phase 3 trial tested a personalized vaccine made from a patient's own immune cells and tumor RNA in 200 people with a high-risk form of eye cancer (uveal melanoma with monosomy 3). After surgery to remove the tumor, half received the vaccine over two years and half were simp…
Matched conditions: UVEAL MELANOMA
Phase: PHASE3 • Sponsor: University Hospital Erlangen • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 22, 2026 12:04 UTC
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Could a liver cancer drug slow eye cancer spread?
Disease control CompletedThis study tested the drug sorafenib (Nexavar) in 32 adults with uveal melanoma that had spread to other parts of the body. The goal was to see if the drug could stop tumors from growing for at least 24 weeks. Sorafenib is already used for other cancers, and researchers wanted to…
Matched conditions: UVEAL MELANOMA
Phase: PHASE2 • Sponsor: University Hospital, Caen • Aim: Disease control
Last updated Jun 23, 2026 11:54 UTC
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New immune cell therapy shows promise for Hard-to-Treat melanoma
Disease control CompletedThis early-phase study tested a new treatment called TBio-4101 for people with advanced melanoma that has not responded to standard therapies. The treatment uses a patient's own immune cells (TILs) that are collected from their tumor, multiplied in a lab, and then given back afte…
Matched conditions: UVEAL MELANOMA
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 18, 2026 11:53 UTC
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New hope for rare eye cancer: IMCgp100 shows promise in advanced uveal melanoma trial
Disease control CompletedThis study tested a new drug called IMCgp100 in 378 adults with a specific genetic type (HLA-A*0201) of advanced uveal melanoma, a rare eye cancer. Participants received either IMCgp100 or one of three standard treatments (dacarbazine, ipilimumab, or pembrolizumab). The main goal…
Matched conditions: UVEAL MELANOMA
Phase: PHASE2 • Sponsor: Immunocore Ltd • Aim: Disease control
Last updated Jun 18, 2026 11:48 UTC
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Early emotional support may ease burden for advanced eye cancer patients
Symptom relief CompletedThis study looked at whether starting supportive care early helps patients with metastatic uveal melanoma, a rare eye cancer that has spread. 162 adults were split into two groups: one received standard cancer care plus early supportive care visits, the other received standard ca…
Matched conditions: UVEAL MELANOMA
Phase: NA • Sponsor: Institut Curie • Aim: Symptom relief
Last updated Jun 23, 2026 20:49 UTC
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Blood test may predict success of liver surgery for rare eye cancer
Knowledge-focused CompletedThis study looked at whether measuring tumor DNA in the blood can help doctors understand how well surgery worked for uveal melanoma that spread to the liver. About 60 adults with this condition had blood samples taken before and after surgery. The goal was to see if changes in t…
Matched conditions: UVEAL MELANOMA
Phase: NA • Sponsor: Institut Curie • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:47 UTC