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New immune cell therapy shows promise for Hard-to-Treat melanoma

NCT ID NCT05628883

First seen Jan 11, 2026 · Last updated Jun 18, 2026 · Updated 27 times

Summary

This early-phase study tested a new treatment called TBio-4101 for people with advanced melanoma that has not responded to standard therapies. The treatment uses a patient's own immune cells (TILs) that are collected from their tumor, multiplied in a lab, and then given back after chemotherapy. The goal was to see if this approach is safe and feasible for patients with various types of melanoma.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

The condition(s) this trial relates to.

acral lentiginous melanoma cutaneous melanoma iris melanoma malignant conjunctival melanoma melanoma metastatic melanoma mucosal melanoma non-cutaneous melanoma ocular melanoma uveal melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.