TREATMENT RESISTANT DEPRESSION
Clinical trials for TREATMENT RESISTANT DEPRESSION explained in plain language.
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Depression drug study halted early: what happened?
Disease control TerminatedThis study looked at the long-term safety and effectiveness of an experimental drug called AXS-05 for people with treatment-resistant depression (depression that hasn't improved with other treatments). The study enrolled 181 adults who either completed a prior AXS-05 study or cur…
Matched conditions: TREATMENT RESISTANT DEPRESSION
Phase: PHASE2 • Sponsor: Axsome Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 05:01 UTC
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Experimental depression drug trial halted early
Symptom relief TerminatedThis study tested whether adding MK-1942 to usual antidepressant medication could help people with treatment-resistant depression. About 99 adults with moderate-to-severe depression who hadn't improved with prior treatments took part. The trial was stopped early, and results are …
Matched conditions: TREATMENT RESISTANT DEPRESSION
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Symptom relief
Last updated May 26, 2026 05:05 UTC
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New hope for stubborn depression? tianeptine trial launched
Symptom relief TerminatedThis study tested the drug tianeptine in 38 adults with major depression that did not improve after at least two standard treatments. Participants took tianeptine for 8 weeks, and researchers measured changes in depression symptoms using a standard questionnaire. The trial was te…
Matched conditions: TREATMENT RESISTANT DEPRESSION
Phase: PHASE4 • Sponsor: Jonathan A. Javitch, MD, PhD • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC