TOTAL HIP ARTHROPLASTY (THA)

This study is testing a new liner (XPEO-E) used in hip replacement surgery to see how well it improves patients' ability to move and reduces pain. About 500 adults who need a total hip replacement will receive the liner and be followed for up to several years. The study collects …

This study tests a new pain medicine called suzetrigine in 210 adults having hip replacement surgery. Half will get the drug and half a placebo for seven days, starting before surgery. The goal is to see if it lowers the amount of opioids needed in the first 48 hours after surger…

This study tests whether starting physical therapy early, combined with a muscle-stimulating device and remote coaching via video calls, can improve walking and strength after hip replacement surgery. About 52 adults aged 50 to 75 having their first hip replacement will be split …

This study tests whether an ultrasound-guided nerve block (called an erector spinae plane block) can reduce pain and the need for morphine after total hip replacement. Sixty adults having hip surgery will be randomly assigned to receive either the nerve block plus standard pain c…

This study looks at whether adding cognitive behavioral therapy (CBT) to standard physical therapy helps people who have had a hip replacement feel less afraid of moving and have less pain. About 100 adults who recently had their first hip replacement and have high fear of moveme…

This study looks at whether adding digital technology to standard physical therapy helps older adults (ages 65-89) recover both thinking skills and physical abilities after hip fracture surgery. About 30 participants will be followed to see if the tech-assisted approach improves …

This study tests whether listening to binaural beats (special sound patterns) or your favorite music for 30 minutes after knee or hip replacement surgery can lower pain and anxiety. Fifty adults having these surgeries will be randomly assigned to one of the two listening options.…

This study tests whether a 12-week digital home exercise program, with or without personal coaching, can help adults aged 65 and older become more physically active after total hip replacement. About 213 participants will be randomly assigned to the digital program, the program p…

This study compares two types of nerve blocks for pain after hip replacement surgery. About 118 adults will receive either an iliopsoas plane block or a PENG block before surgery. The goal is to see if the newer block works as well for pain control and recovery.

This study tests whether adding strength training with blood flow restriction to standard rehab helps people who had a hip replacement regain muscle strength and reduce pain. Thirty adults who had surgery within the last month will participate. The goal is to see if this approach…

This study compares two types of nerve blocks for pain relief after hip replacement surgery. About 130 adults having elective hip replacement will be randomly assigned to receive either the experimental psoas sheath block or the standard fascia iliaca block. The goal is to see wh…

This study looks at hip and knee tissue from 1000 people having joint replacement surgery for osteoarthritis. Researchers want to measure levels of rare metals and immune markers in the joint tissue and blood. The goal is to find clues that could lead to better treatments, like m…