STAGE IV NON-SMALL CELL LUNG CANCER
Clinical trials for STAGE IV NON-SMALL CELL LUNG CANCER explained in plain language.
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Radiation boost tested to supercharge lung cancer immunotherapy
Disease control CompletedThis study tested whether adding a short, high-dose course of radiation therapy could improve the effectiveness of immunotherapy for people with stage IV non-small cell lung cancer. It involved 45 patients who were already receiving immunotherapy. The goal was to see if the radia…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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New drug combo tested as last hope for tough lung cancers
Disease control CompletedThis study tested a combination of two oral drugs, auranofin and sirolimus, for patients with advanced or returning lung cancer who had run out of standard treatment options. The main goals were to find the safest dose and see if the treatment could slow the cancer's growth. The …
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New drug duo tested in fight against tough cancers
Disease control CompletedThis study tested whether combining an experimental drug (sEphB4-HSA) with an approved immunotherapy (pembrolizumab) could help control advanced lung or head/neck cancers that had worsened after standard chemotherapy. It involved 42 patients who received both drugs by IV infusion…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Vaccine-Immunotherapy combo tested in Tough-to-Treat lung cancer
Disease control CompletedThis study tested whether combining a cancer vaccine (TG4010) with an immunotherapy drug (nivolumab) could help control advanced non-small cell lung cancer in patients whose previous treatments had stopped working. The vaccine aims to train the immune system to recognize and atta…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: Megan Daly, MD • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New combo attack on brain tumors shows promise
Disease control CompletedThis small, early-stage study tested the safety of combining two treatments for cancer that has spread to the brain: an immunotherapy drug (pembrolizumab) and a very precise form of radiation (stereotactic radiosurgery). The goal was to see if using them together was safe and cou…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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First human test of new lung cancer drug combo completed
Disease control CompletedThis study tested the safety and side effects of a new drug, ONO-7475, when given alongside the standard drug osimertinib. It involved 78 adults with advanced or recurrent non-small cell lung cancer that has a specific genetic change (EGFR mutation). The main goal was to find a s…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: Ono Pharmaceutical Co. Ltd • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC