STAGE IV NON-SMALL CELL LUNG CANCER
Clinical trials for STAGE IV NON-SMALL CELL LUNG CANCER explained in plain language.
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New combo therapy tested for common lung cancer mutation
Disease control CompletedThis study tested whether adding cetuximab to afatinib helps people with advanced EGFR-mutant non-small cell lung cancer live longer compared to afatinib alone. It included 174 newly diagnosed or recurrent patients. The goal was to see if the combination improves survival and del…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE2, PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 26, 2026 04:43 UTC
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New combo therapy shows promise for brain metastases
Disease control CompletedThis early study tested whether combining an immunotherapy drug (pembrolizumab) with precise radiation (stereotactic radiosurgery) is safe for people with melanoma or lung cancer that has spread to the brain. 25 participants received the combination. The main goal was to check fo…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated May 26, 2026 04:43 UTC
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New drug cocktail shows promise for tough lung cancers
Disease control CompletedThis study tested two drugs, auranofin and sirolimus, together in 29 people with advanced lung cancer that had stopped responding to standard treatments. The goal was to find the best dose and see if the combination could slow or stop cancer growth. The trial focused on safety an…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 26, 2026 04:41 UTC
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New drug duo targets hard-to-treat lung cancer in early trial
Disease control CompletedThis early-phase study tested a new drug called ONO-7475 combined with the standard targeted therapy osimertinib in 78 people with advanced EGFR-mutant non-small cell lung cancer that could not be treated with radiation. The main goal was to check safety and find the right dose. …
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: Ono Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 04:40 UTC
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Radiation boosts immunotherapy in advanced lung cancer trial
Disease control CompletedThis study tested whether adding high-dose, precisely targeted radiation to standard immunotherapy could help control advanced non-small cell lung cancer that has spread. Forty-five adults with stage IV disease who were already on immunotherapy received radiation to some tumors. …
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated May 26, 2026 04:39 UTC
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Experimental combo shows promise in Tough-to-Treat lung cancer
Disease control CompletedThis study tested a new combination treatment for people with advanced non-small cell lung cancer that had already been treated. The treatment combined a cancer vaccine (TG4010) with an immunotherapy drug (nivolumab) to help the immune system fight the cancer. The trial included …
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: Megan Daly, MD • Aim: Disease control
Last updated May 26, 2026 04:39 UTC
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Promising combo targets tough cancers in early trial
Disease control CompletedThis study tested a combination of two drugs—sEphB4-HSA and pembrolizumab—in 42 people with advanced non-small cell lung cancer or head & neck cancer that had spread or returned. The goal was to see if the combo could shrink tumors better than standard treatments. Participants ha…
Matched conditions: STAGE IV NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated May 26, 2026 04:31 UTC