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Promising combo targets tough cancers in early trial

NCT ID NCT03049618

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 36 times

Summary

This study tested a combination of two drugs—sEphB4-HSA and pembrolizumab—in 42 people with advanced non-small cell lung cancer or head & neck cancer that had spread or returned. The goal was to see if the combo could shrink tumors better than standard treatments. Participants had already tried other therapies, including chemotherapy. The trial is now complete, and results help guide future research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

Conditions

Explore the condition pages connected to this study.