STAGE III PANCREATIC CANCER AJCC V8
Clinical trials for STAGE III PANCREATIC CANCER AJCC V8 explained in plain language.
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Sound waves could supercharge chemo against tough pancreatic cancer
Disease control OngoingThis study tests a new method called sonoporation, which uses ultrasound and tiny gas bubbles to help chemotherapy drugs get into cancer cells more effectively. About 120 adults with advanced pancreatic cancer will receive either standard chemotherapy alone or chemotherapy plus s…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Flemming Forsberg • Aim: Disease control
Last updated May 26, 2026 08:23 UTC
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New drug cocktail takes aim at tough pancreatic cancer
Disease control OngoingThis early-phase study tests a new drug combination for people with advanced pancreatic cancer that has a specific marker (mesothelin). The treatment pairs a targeted chemotherapy (anetumab ravtansine) with immunotherapy drugs (nivolumab, ipilimumab) and/or standard chemo (gemcit…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:18 UTC
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New drug cocktail aims to starve pancreatic tumors
Disease control OngoingThis early-phase study tests a combination of two drugs—calaspargase pegol-mknl and cobimetinib—in people with advanced pancreatic cancer that has spread. The goal is to find the safest dose and see if the combo can control the disease by cutting off the cancer cells' food supply…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Experimental drug combo targets Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests a new drug (M6620) combined with a standard chemotherapy (irinotecan) in adults with advanced solid tumors that have spread or can't be removed by surgery. The main goal is to find the safest dose and check for side effects. About 66 participants with…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New combo targets Hard-to-Treat pancreatic cancer
Disease control TerminatedThis early-stage trial tests a new drug called CA-4948 added to standard chemotherapy for people with pancreatic cancer that has spread or can't be removed. The goal is to find the safest dose and see if the combination can shrink tumors or stop them from growing. About 43 adults…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Personalized cell therapy trial for advanced cancers withdrawn before enrollment
Disease control TerminatedThis early-stage trial aimed to test the safety and effectiveness of STIL101, a personalized cell therapy made from a patient's own tumor-fighting T cells, for several advanced cancers including pancreatic, colorectal, kidney, cervical, and melanoma. The treatment involved collec…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New drug combo targets BRCA cancers in early trial
Disease control OngoingThis early-phase trial tests a combination of two drugs—niraparib (a PARP inhibitor) and dostarlimab (an immunotherapy)—in people with BRCA-mutated breast, pancreas, or ovarian cancers that have spread or cannot be surgically removed. The goal is to see if the combo can shrink tu…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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Tablet-Based exercise may boost strength in pancreatic cancer patients
Symptom relief OngoingThis study looks at whether a supervised, at-home resistance training program done via tablet is safe and helpful for people with advanced pancreatic cancer. About 25 participants will do guided exercises while receiving chemotherapy or recovering from surgery. The goal is to see…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 08:22 UTC