STAGE I PROSTATE CANCER AJCC V8
Clinical trials for STAGE I PROSTATE CANCER AJCC V8 explained in plain language.
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Aspirin and immune boosters could help fight prostate cancer before surgery
Disease control OngoingThis phase 2 trial tests whether giving a combination of enteric-coated aspirin, rintatolimod, and interferon-alpha 2b before prostate cancer surgery can boost the immune system's attack on tumors. The study involves 12 men with localized prostate cancer who are scheduled for sur…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 23, 2026 12:09 UTC
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Could a common mushroom help fight prostate cancer?
Disease control TerminatedThis phase 2 trial tests whether white button mushroom extract can lower PSA levels in men with prostate cancer that has returned after treatment or is low-risk and not yet treated. About 133 men will take the supplement or be observed. The goal is to see if the mushroom affects …
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 22, 2026 11:55 UTC
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Promising prostate cancer trial pulled before it even started
Disease control TerminatedThis study was designed to see if adding the immunotherapy drug pembrolizumab to standard hormone therapy and radiation could improve outcomes for men with high-risk prostate cancer that hasn't spread. The trial was withdrawn before enrolling any participants, so no results are a…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Jun 17, 2026 12:07 UTC
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Shorter radiation blasts may be safer and just as effective for prostate cancer
Disease control OngoingThis study tests whether a shorter, higher-dose radiation schedule (hypofractionated) works as well as the standard longer course for men with prostate cancer who have had their prostate removed. About 186 men will be randomly assigned to one of the two radiation plans. The main …
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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Could a tiny dose of this drug help men avoid prostate surgery?
Disease control OngoingThis study tests whether a very low dose of apalutamide, taken for 3-4 weeks before prostate removal surgery, can lower PSA levels in men with early-stage prostate cancer. The goal is to see if this approach might allow some men to delay or avoid surgery or radiation in the futur…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 09, 2026 12:10 UTC
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Fasting during radiation may ease treatment side effects
Symptom relief OngoingThis study compares time-restricted eating (intermittent fasting) with standard nutritional counseling in cancer patients receiving radiation or chemoradiation for prostate, cervical, or rectal cancers. The goal is to see if fasting reduces treatment side effects and improves how…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 22, 2026 12:08 UTC
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New bladder tuck may help men stay dry after prostate cancer surgery
Symptom relief TerminatedThis study looks at whether adding a simple bladder support step (vesicopexy) to standard robotic prostate cancer surgery helps men regain bladder control faster and improves their quality of life. About 196 men with early-stage prostate cancer will take part. The main goal is to…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Jun 22, 2026 12:04 UTC
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New lifestyle program aims to boost quality of life for prostate cancer patients
Symptom relief OngoingThis pilot study tests a lifestyle intervention called Watchful Living for Black and Hispanic prostate cancer patients on active surveillance and their partners. The program includes nutrition counseling, an exercise plan, and telephone coaching to improve quality of life, physic…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 22, 2026 11:55 UTC
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Which radiation is easier on prostate cancer patients?
Symptom relief OngoingThis study compares two types of radiation therapy for men with early-stage prostate cancer that hasn't spread. One method places a tiny radioactive seed directly into the prostate for a few minutes, while the other delivers radiation from outside the body in five sessions. The g…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Symptom relief
Last updated Jun 09, 2026 12:07 UTC
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Prostate cancer patients try mediterranean diet before surgery in small feasibility study
Knowledge-focused OngoingThis small study tests whether men with intermediate-risk prostate cancer can follow a Mediterranean diet for a few weeks before their scheduled prostate removal surgery. The main goal is to see if this approach is practical and well-tolerated, not to cure the cancer. Researchers…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:55 UTC
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Prostate cancer treatment may harm your heart – new study investigates
Knowledge-focused OngoingThis study looks at how certain hormone therapies for prostate cancer affect the heart. It compares two drugs, leuprolide and relugolix, given alongside radiation. The goal is to understand why some men develop heart problems and find ways to predict and reduce that risk. About 9…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:06 UTC
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Can a couple's lifestyle program reduce prostate cancer disparities?
Knowledge-focused OngoingThis study tests a lifestyle program for African American men who have finished prostate cancer treatment and their spouses or partners. The goal is to see if the program can improve quality of life, diet, physical activity, and partner support. Only 6 participants were enrolled,…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC
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Couples' coping: new study tracks stress and health in black prostate cancer survivors
Knowledge-focused OngoingThis study looks at how day-to-day stress, social support, and healthy habits like exercise and diet affect Black prostate cancer survivors and their partners. About 200 couples will use a smartphone app to report their activities and feelings throughout the day. The goal is to u…
Matched conditions: STAGE I PROSTATE CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC