Aspirin and immune boosters could help fight prostate cancer before surgery
NCT ID NCT03899987
First seen May 05, 2026 · Last updated Jun 22, 2026 · Updated 6 times
Summary
This phase 2 trial tests whether giving a combination of enteric-coated aspirin, rintatolimod, and interferon-alpha 2b before prostate cancer surgery can boost the immune system's attack on tumors. The study involves 12 men with localized prostate cancer who are scheduled for surgery. The main goal is to see if these drugs increase cancer-fighting immune cells in the tumor.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
enteric-coated aspirin, rintatolimod, and interferon-alpha 2b
What this could lead to
If successful, this could point toward a new pre-surgery treatment that helps the immune system fight prostate cancer and lowers the chance of it coming back.
What could go wrong
This is a very small early-phase trial with only 12 participants, so results may not apply broadly. The drugs may cause side effects like flu-like symptoms or bleeding risks from aspirin.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.