Spina bifida

This trial tests whether metformin, a drug that improves insulin sensitivity, can help overweight children with neurological or neuromuscular conditions. These children often face mobility challenges that lead to a sedentary lifestyle and weight gain. The study compares six month…

This study tested a new type of leg brace designed to help children with cerebral palsy and other movement disorders walk more easily. The brace was custom-made for each child and could be adjusted to provide different kinds of support. Researchers measured how well children walk…

This study tests whether a new high-intensity exercise program is feasible and can improve dynamic balance and physical activity in adolescents with cerebral palsy or spina bifida. Participants will perform a series of exercises twice a week, with researchers measuring walking sp…

This study tested whether a high-intensity exercise program, run by physical therapy students, can help people with neurologic disabilities move better in everyday life. Fifteen participants with conditions like cerebral palsy, stroke, or spinal cord injury completed the program.…

This study tested a 12-week exercise program set to music for adults with physical disabilities like spinal cord injury, stroke, or Parkinson's disease. Participants exercised three times a week via video calls, doing movements adapted to their ability. The goal was to see if the…

This study tested prefabricated carbon fiber ankle-foot orthoses (AFOs) in 65 children and teenagers with conditions like cerebral palsy, spina bifida, or spinal cord injuries that affect walking. Researchers measured stride length, walking speed, and user satisfaction by compari…

This study looked at two community-based wellness programs for adults with disabilities like spina bifida, cerebral palsy, spinal cord injury, and traumatic brain injury. Researchers measured changes in health, mood, quality of life, and healthcare costs over up to 24 months. The…

This study looks at how lung function, respiratory muscle strength, balance, and quality of life relate in Paralympic athletes. Researchers will measure breathing capacity, muscle strength, and balance in 24 athletes from sports like athletics, swimming, archery, and wheelchair b…

This study looks at how young people with conditions like cerebral palsy, spina bifida, and spinal cord injury move from pediatric to adult medical care. Researchers will review medical records from the past 10 years and interview patients who have already made the switch. The go…

This study looked at 36 adults with spina bifida to understand why they often have bowel issues. Researchers took small tissue samples from the colon during a routine scope and measured how the rectum works. The goal was to see if nerve damage affects the gut's lining and nerves,…

This study looked at 21 pregnant women and their babies to understand how surgery before birth changes the immune system. The goal was to find out if immune system activation might cause early labor. Researchers collected blood samples and studied the placenta to track immune cha…