SOLID TUMORS, ADULT
Clinical trials for SOLID TUMORS, ADULT explained in plain language.
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New hope for advanced cancer: experimental drug HMPL-A580 enters human trials
Disease control Recruiting nowThis study tests a new drug called HMPL-A580 in adults with advanced or metastatic solid tumors that cannot be removed by surgery. The main goals are to find a safe dose and see if the drug can shrink tumors. About 186 participants will take part in this early-phase trial.
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated May 26, 2026 11:11 UTC
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New drug STX-478 targets mutant cancers in first human trial
Disease control Recruiting nowThis study tests a new drug, STX-478, designed to attack cancer cells with a specific genetic change (PI3Kα mutation). It is for adults with advanced solid tumors, including breast cancer, that have not responded to other treatments. The study will first test STX-478 alone, then …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 26, 2026 11:09 UTC
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New combo targets Hard-to-Treat cancers with STK11 mutation
Disease control Recruiting nowThis study tests a new drug called TNG260 combined with an immunotherapy (pembrolizumab) in people with advanced solid tumors that have a specific gene change (STK11 mutation). The goal is to find the safest dose and see if the combination can shrink tumors. About 126 adults with…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 11:04 UTC
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New cancer drug DCR-PDL1 enters first human safety tests
Disease control Recruiting nowThis early-stage study is testing a new drug called DCR-PDL1 in about 32 adults with advanced solid tumors that have not responded to standard treatments. The main goal is to check the drug's safety and find the best dose by giving it through an IV in increasing amounts. Research…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control
Last updated May 26, 2026 11:03 UTC
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Immune cells from your own tumor could fight cancer – early trial begins
Disease control Recruiting nowThis early-phase study tests a new treatment called GT101 for adults with solid tumors that have spread or come back. The therapy uses immune cells taken from the patient's own tumor, multiplied in a lab, and then given back along with chemotherapy and immune-boosting drugs. The …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated May 26, 2026 11:01 UTC
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New pill targets hard-to-treat cancers with KRAS mutation
Disease control Recruiting nowThis study tests an experimental drug called ABSK141 in about 400 adults with advanced solid tumors that have a specific KRAS G12D mutation. The goal is to find a safe dose and see if the drug can shrink tumors or slow their growth. Participants must be 18 or older and have cance…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Abbisko Therapeutics Co, Ltd • Aim: Disease control
Last updated May 26, 2026 11:01 UTC
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New smart chemo targets HER-2 cancers in early trial
Disease control Recruiting nowThis early-phase study tests HF158K1, a chemotherapy drug wrapped in a special coating that targets HER-2, a protein on some cancer cells. The goal is to see if it is safe and to find the right dose for people with advanced solid tumors that have HER-2. About 84 adults will take …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: HighField Biopharmaceuticals Corporation • Aim: Disease control
Last updated May 26, 2026 10:35 UTC
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New drug HMPL-A251 targets Hard-to-Treat HER2 cancers in early trial
Disease control Recruiting nowThis study tests a new drug called HMPL-A251 in adults with advanced or metastatic solid tumors that have a protein called HER2. The main goals are to find a safe dose and see if the drug can shrink tumors. About 147 participants will receive the drug, and researchers will monito…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Immune cells take on tough tumors in early trial
Disease control Recruiting nowThis early-phase study tests a personalized cell therapy (TIL injection) for people with advanced solid tumors that have spread or come back. About 12 adults will receive their own immune cells, grown in a lab, after a short course of chemotherapy. The main goal is to check safet…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New scan could reveal hidden cancers
Diagnosis Recruiting nowThis early-phase study tests a new radioactive tracer called FAP-2286 to see how well it can find cancer that has spread in adults with solid tumors. About 191 participants will get an injection of the tracer and then have a PET scan. The goal is to measure safety and how accurat…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated May 20, 2026 11:55 UTC