SOLID TUMORS, ADULT
Clinical trials for SOLID TUMORS, ADULT explained in plain language.
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New drug aims to shrink hard-to-treat HER2 cancers
Disease control Recruiting nowThis study tests a new drug called HMPL-A251 in adults with advanced or spreading solid tumors that have a protein called HER2. The goal is to find a safe dose and see if the drug can shrink tumors. About 147 participants will receive the drug, and researchers will monitor side e…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated May 17, 2026 00:47 UTC
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New hope for Hard-to-Treat cancers? early trial launches
Disease control Recruiting nowThis early-phase study tests a new drug called HMPL-A580 in adults with advanced or metastatic solid tumors that cannot be removed by surgery. The main goals are to find a safe dose and see if the drug can shrink tumors. About 186 participants will take part in this first-in-huma…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated May 17, 2026 00:43 UTC
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New drug DCR-PDL1 enters human testing for solid tumors
Disease control Recruiting nowThis early-stage study is testing a new drug, DCR-PDL1, in 32 adults with solid tumors that have not responded to standard treatments. The main goal is to check the drug's safety and find the best dose. Participants will receive the drug through an IV and be closely monitored for…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control
Last updated May 17, 2026 00:28 UTC
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Immune cells from your own tumor could fight cancer
Disease control Recruiting nowThis early-phase study tests a new treatment called GT101 for people with advanced solid tumors that have spread or come back. GT101 uses immune cells taken from the patient's own tumor, multiplied in a lab, and then given back to the patient. The study aims to check if this appr…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New combo targets Hard-to-Treat cancers with STK11 mutation
Disease control Recruiting nowThis study is for adults with advanced solid tumors that have a specific genetic change called STK11 mutation. The goal is to test a new drug, TNG260, given alone or with an immunotherapy drug (pembrolizumab). Researchers want to find the best dose, check safety, and see if the c…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New drug targets tough cancers in 401-Patient trial
Disease control Recruiting nowThis study tests a new drug called ABSK141 in 401 adults with advanced solid tumors that have a specific gene change called KRAS G12D. The goal is to see if the drug is safe, tolerable, and how well it works. The study is open-label, meaning everyone knows they are getting the dr…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Abbisko Therapeutics Co, Ltd • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Immune cell attack: new hope for Hard-to-Treat cancers?
Disease control Recruiting nowThis early-stage trial tests an experimental therapy using a patient's own immune cells (TILs) to fight advanced solid tumors that have spread or come back. About 12 adults with certain cancers will receive the treatment after chemotherapy. The main goal is to check safety and si…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New smart chemo aims to hit HER-2 cancers harder with fewer side effects
Disease control Recruiting nowThis early-phase study is testing HF158K1, a chemotherapy drug wrapped in a special coating that targets HER-2, a protein found on some cancer cells. The goal is to see if it is safe and to find the best dose for people with advanced solid tumors that have not responded to other …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: HighField Biopharmaceuticals Corporation • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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New drug targets mutations in Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new drug, STX-478, designed to attack cancer cells with a specific genetic change (PI3Kα mutation). It is for adults with advanced solid tumors, including breast cancer, that have not responded to other treatments. The study will test the drug alone or combined…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 07, 2026 18:39 UTC
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New scan agent could spot hidden cancers
Diagnosis Recruiting nowThis study tests a new radioactive tracer called FAP-2286 to see if it can better detect cancer that has spread in adults with solid tumors. About 191 participants will receive the tracer and then have a PET scan. The goal is to measure how safe the tracer is and how well it high…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated May 17, 2026 00:46 UTC