SOLID TUMORS, ADULT
Clinical trials for SOLID TUMORS, ADULT explained in plain language.
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New cancer drug enters first human safety testing
Disease control Recruiting nowThis is the first human study testing a new cancer drug called DCR-PDL1, given through an IV. Researchers will enroll 32 adults with advanced solid tumors that haven't responded to standard treatments. The main goal is to find the safest dose by testing four different levels and …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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First human test of new Cancer-Fighting immune cells begins
Disease control Recruiting nowThis early-stage study is testing the safety of a personalized immune cell therapy called TIL injection (GT101) for adults with metastatic or recurrent solid tumors. Researchers will collect a patient's own tumor-fighting immune cells, grow them in a lab, and reinfuse them back i…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New targeted cancer drug enters human trials for advanced tumors
Disease control Recruiting nowThis early-stage study is testing a new targeted cancer drug called STX-478, both alone and in combination with other approved cancer therapies. It aims to find a safe dose and see if it can help control advanced solid tumors, particularly breast cancer, that have a specific gene…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New drug combo targets Hard-to-Treat mutated cancers
Disease control Recruiting nowThis study is testing a new oral drug called TNG260, given alone and with the immunotherapy pembrolizumab, for people with advanced solid tumors that have a specific genetic change (STK11 mutation). The main goals are to find a safe and effective dose and to see if the treatment …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New cancer drug enters human testing for advanced tumors
Disease control Recruiting nowThis early-stage study is testing a new drug called HMPL-A580 in adults with advanced solid tumors that cannot be removed by surgery. The main goals are to find a safe dose and see if the drug shows any early signs of fighting the cancer. Researchers will monitor participants clo…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for Tough-to-Treat cancers? early trial tests novel drug
Disease control Recruiting nowThis is an early-stage study testing a new drug called HMPL-A251 in adults with advanced or spreading HER2-positive solid tumors that cannot be removed by surgery. The main goals are to find a safe dose, check for side effects, and get an early look at whether the drug can help s…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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First human trial targets 'Undruggable' cancer mutation
Disease control Recruiting nowThis study is testing a new oral drug called ABSK141 in people with advanced solid tumors that have a specific genetic change called KRAS G12D. The main goals are to find a safe dose, see how the body processes the drug, and check if it can help control cancers like colorectal, l…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Abbisko Therapeutics Co, Ltd • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New scan could spot hidden cancer spread
Diagnosis Recruiting nowThis early-stage trial is testing a new imaging tracer called FAP-2286 to see if it can better detect cancer that has spread (metastasized) in people with solid tumors. The study will enroll about 191 adults with cancers like breast, prostate, pancreatic, and colon cancer. Resear…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated Mar 23, 2026 15:19 UTC