SLEEP APNEA

This study looks at whether using a CPAP machine to treat sleep apnea soon after an ischemic stroke can reduce the risk of another stroke, heart attack, or death within 6 months. About 3,000 adults who had a stroke and have sleep apnea are taking part. The goal is to see if this …

This study checks if a Withings smartwatch can accurately detect sleep apnea by measuring movement, heart rate, breathing, and blood oxygen. About 220 adults who are already scheduled for a hospital sleep test will wear the watch overnight. The goal is to see if the watch can rep…

This study looks at whether adding CPAP therapy (a machine that helps you breathe during sleep) to standard lifestyle changes can lower the risk of developing diabetes in people who have prediabetes and are overweight. About 174 participants will be followed for 6 months to see i…

This study tests whether showing sleep apnea patients how their CPAP machine use compares to other patients helps them use it more regularly. About 186 adults who have been on CPAP for at least three months will be randomly assigned to get either their own usage data or their dat…

This study tests three different drugs—sivopixant, acetazolamide, and SASS-001—to see if they can reduce the number of breathing pauses (apneas) during sleep in adults with central sleep apnea. About 60 participants with heart conditions will receive one of the drugs or a placebo…

This study collects blood, urine, and tissue samples from 500 adults with obesity to help researchers learn why people gain or lose weight, and why some regain weight after treatment. Participants must be over 18 and have a BMI of 30 or higher. The samples will be stored for up t…

This study looks at how normal sleep changes and sleep apnea might increase the risk of Alzheimer's disease in healthy older adults. Researchers will monitor sleep and brain changes in 158 people aged 55-75 over two years. The goal is to find ways to prevent Alzheimer's by improv…

This study surveys 1,000 medical trainees (students, residents, fellows) who work on-call shifts. It asks about their sleep habits, knowledge of sleep health, and how shift work impacts their sleep quality and daily performance. The goal is to gather information, not to test a tr…

This study looks at how sleep problems like sleep apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural areas of the southern U.S. About 3,680 adults already in a larger health study will wear a sleep tracker and answer questionnaires. The goal…

This study looks at whether dopamine levels and certain genes are linked to sleep breathing disorders like sleep apnea. About 100 adults with suspected sleep issues will have an overnight sleep test and a blood draw. The goal is to better understand what causes these conditions, …

This study looks at how sleep apnea might cause pre-diabetes in overweight people. Researchers will measure stress hormones in the blood of 300 adults with sleep apnea and pre-diabetes. The goal is to understand the connection, not to test a treatment.

This study aimed to test a new wearable wireless device for monitoring central sleep apnea in infants and children aged 1 month to 5 years. The device was to be worn overnight alongside standard hospital sensors to check its accuracy. However, the study was withdrawn before any p…

This study looks at 100 adults with sleep bruxism (teeth grinding during sleep) to understand how it relates to sleep quality, heart health, thyroid function, and mental well-being. Participants will undergo sleep monitoring and fill out questionnaires. No treatment is given; the…