SLEEP APNEA

This study tests whether using a CPAP machine to treat sleep apnea shortly after an ischemic stroke can reduce the risk of another stroke, heart attack, or death within 6 months. It also looks at whether CPAP improves overall recovery and brain function. Over 3,000 participants a…

This study tests whether Withings bathroom scales can accurately measure pulse wave velocity (PWV), a key indicator of vascular stiffness. Researchers will compare readings from the scales with a standard medical device in 176 adults, including those with high blood pressure, sle…

This study planned to test a new wearable wireless device that wraps around a child's abdomen to monitor central sleep apnea. It would have involved 15 children aged 1 month to 5 years already undergoing standard sleep studies. The device's accuracy and comfort would have been co…

This study checks if a Withings smartwatch can accurately detect sleep apnea compared to a full hospital sleep test. About 220 adults who are already scheduled for a sleep test will wear the watch overnight. The goal is to see if the watch can help screen more people for sleep ap…

This study looks at whether adding CPAP (a machine that helps you breathe at night) to a healthy lifestyle program can lower the risk of diabetes in people with prediabetes and sleep apnea. About 174 overweight or obese adults with both conditions will be followed for 6 months. T…

This study aimed to see if taking branched-chain amino acids (BCAAs) could improve oxygen levels during sleep in people with sleep apnea. The researchers planned to include adults with confirmed sleep apnea but exclude those with severe cases. However, the study was withdrawn bef…

This Phase 2A study tests three drugs—sivopixant, acetazolamide, and SASS-001—in 60 adults with sleep apnea that has a central component (where the brain fails to signal breathing). The goal is to see if these drugs can reduce the number of breathing pauses during sleep. Particip…

This study looks at whether showing sleep apnea patients how their CPAP machine use compares to other patients helps them use it more. About 186 people who have been on CPAP for at least three months will be split into two groups. One group gets only their own usage data; the oth…

This study collects blood, urine, and tissue samples from 500 adults with obesity who are undergoing weight-loss treatments or have had bariatric surgery. The goal is to create a repository that researchers can use to study why people gain or lose weight, why some regain weight, …

This study looks at 100 adults with sleep bruxism (teeth grinding during sleep) to understand how it relates to sleep quality, heart health, thyroid function, and mental well-being. Participants will have sleep tests and questionnaires, and some will receive a drug called Opipram…

This study uses a 30-40 minute online survey to understand how being on call affects sleep in 1,000 medical trainees (students, residents, fellows). It looks at sleep quality, quantity, and disruption to body rhythms. The goal is to gather knowledge to improve sleep health for he…

This study looks at whether dopamine levels and certain genes affect the risk and severity of sleep breathing disorders like sleep apnea. Researchers will monitor 100 adults overnight and take blood samples to measure dopamine and check for genetic variations. The goal is to bett…

This study looks at how normal sleep changes and sleep apnea in older adults might increase the risk of Alzheimer's disease. Researchers will monitor the sleep and brain health of 158 cognitively healthy people aged 55-75 over two years. The goal is to find out which sleep proble…

This study looks at why overweight adults with sleep apnea have a higher risk of blood sugar problems and diabetes. Researchers will compare people with and without sleep apnea, and test whether using a CPAP machine or just extra oxygen at night can improve how the body handles s…

This study looks at how sleep apnea might contribute to the development of pre-diabetes in overweight or obese adults. Researchers will measure stress hormones in the blood to understand the connection. The goal is to learn more about the early steps that lead to diabetes, not to…

This study looks at how sleep problems like apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural southern areas. About 3,680 adults already in a larger health study will wear sleep trackers and answer questionnaires. The goal is to understand …