SICKLE CELL ANEMIA
Clinical trials for SICKLE CELL ANEMIA explained in plain language.
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New sickle cell drug shows early promise in safety trial
Disease control CompletedThis early-stage study tested a new drug called Pociredir (FTX-6058) in 45 adults with sickle cell disease. The main goal was to check if the drug is safe and how the body processes it. Researchers also looked at whether it could increase fetal hemoglobin, which may help reduce s…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE1 • Sponsor: Fulcrum Therapeutics • Aim: Disease control
Last updated May 26, 2026 11:29 UTC
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One donor, two transplants: new hope for patients with blood cancer and kidney failure
Disease control CompletedThis study tested a combined bone marrow and kidney transplant from a partially matched family donor for 10 people with both a serious blood disorder and chronic kidney disease. The goal was to treat both conditions with one donor, potentially reducing the need for lifelong anti-…
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 18, 2026 12:01 UTC
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Can a new drug tame sickle cell pain in kids?
Symptom relief CompletedThis study tested a drug called canakinumab (ACZ885) in 49 children and young adults (ages 8-20) with sickle cell anemia to see if it could reduce their daily pain. Participants rated their pain on a scale of 0 to 10, and researchers compared changes over 12 weeks between those w…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 26, 2026 11:35 UTC
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Sickle cell lung danger: landmark study tracks hidden heart risk
Knowledge-focused CompletedThis study looked at nearly 1,000 adults with sickle cell anemia to find out how many also develop pulmonary hypertension (high blood pressure in the lungs). Participants had heart ultrasounds and blood tests, then were followed by phone for up to 3 years. The goal was to learn h…
Matched conditions: SICKLE CELL ANEMIA
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 26, 2026 11:36 UTC
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Quick brain test may help detect thinking issues in sickle cell patients
Knowledge-focused CompletedThis study tested whether the Montreal Cognitive Assessment (MoCA), a short mental quiz, can reliably detect cognitive impairment in adults with sickle cell disease. Researchers compared MoCA results with a full set of detailed thinking tests in 65 participants. The goal is to fi…
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 26, 2026 11:34 UTC
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Sickle cell study reveals blood vessel clues
Knowledge-focused CompletedThis study looked at how problems with small and large blood vessels relate to the severity of sickle cell disease in adults. Researchers measured blood flow and stiffness in the vessels of 49 participants. They also checked blood and oxidative stress markers. The goal was to bet…
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC