SICKLE CELL ANEMIA
Clinical trials for SICKLE CELL ANEMIA explained in plain language.
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One-Shot CRISPR cure trial for devastating blood diseases
⭐️ CURE ⭐️ Recruiting nowThis study is testing a single treatment using the patient's own stem cells that have been genetically modified with CRISPR technology. The goal is to see if this one-time therapy can eliminate the need for lifelong blood transfusions in beta-thalassemia patients and stop painful…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE3 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: ⭐️ CURE ⭐️
Last updated Mar 25, 2026 14:08 UTC
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Weekly pill trial offers hope for sickle cell bone pain
Disease control Recruiting nowThis study is testing if a weekly pill called alendronate is safe and tolerable for adults with sickle cell disease who have a painful bone condition called osteonecrosis (bone death). Researchers will enroll about 30 participants to take the pill for 6 months to see if it helps …
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE2 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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Researchers check if measles vaccine works for kids with sickle cell
Knowledge-focused Recruiting nowThis study aims to understand if children with sickle cell disease develop adequate protection against measles after receiving their standard measles vaccines. Researchers will measure antibody levels in about 130 children before vaccination and again at 4 and 8 weeks after each …
Matched conditions: SICKLE CELL ANEMIA
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Apr 03, 2026 21:25 UTC
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Researchers track future fertility in young sickle cell patients on common drug
Knowledge-focused Recruiting nowThis long-term study follows 250 adolescents and young adults with sickle cell anemia to understand how the medication hydroxyurea affects their growth, puberty development, and future ability to have children. Researchers will monitor participants over time through regular check…
Matched conditions: SICKLE CELL ANEMIA
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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NIH hunts for new sickle cell drugs in blood samples
Knowledge-focused Recruiting nowThis study aims to find new drug treatments for sickle cell disease by collecting small blood samples from volunteers. Researchers will test these samples against thousands of existing compounds to see if any can prevent the red blood cell damage that causes the disease. The stud…
Matched conditions: SICKLE CELL ANEMIA
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:27 UTC