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New pill could boost red blood cells in sickle cell patients

NCT ID NCT07282210

First seen Jan 06, 2026 · Last updated May 20, 2026 · Updated 22 times

Summary

This study tests an experimental drug called SIL-8301 (senicapoc) in people with sickle cell disease who have low hemoglobin and few pain crises. About 105 participants aged 16-35 will take either the drug or a placebo daily for 24 weeks, while continuing their usual hydroxyurea treatment. The main goal is to see if the drug can raise hemoglobin levels by at least 1 g/dL, which could help reduce anemia and related complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Conditions

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