New pill could boost red blood cells in sickle cell patients

NCT ID NCT07282210

First seen Jan 06, 2026 · Last updated May 06, 2026 · Updated 21 times

Summary

This study tests an experimental drug called SIL-8301 (senicapoc) in about 105 adults with sickle cell disease who have severe anemia and few pain crises. Participants take the drug or a placebo daily for 24 weeks, while continuing their usual hydroxyurea treatment. The main goal is to see if the drug raises hemoglobin levels by at least 1 g/dL, which could reduce complications and improve quality of life.

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