SICKLE CELL ANEMIA
Clinical trials for SICKLE CELL ANEMIA explained in plain language.
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New antibody could boost cure rate for devastating blood diseases
⭐️ CURE ⭐️ OngoingThis study is testing if adding a new antibody drug called briquilimab (JSP191) to a blood stem cell transplant makes the treatment more successful for people with sickle cell disease or beta-thalassemia. The transplant is a potential cure, and researchers want to see if the drug…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE1, PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: ⭐️ CURE ⭐️
Last updated Mar 27, 2026 12:38 UTC
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New hope to stop strokes in young sickle cell patients
Disease control OngoingThis study aims to prevent strokes in young adults with sickle cell anemia in Nigeria. Researchers will monitor 250 participants aged 16-25 for brain injuries and test whether a medication called hydroxyurea can safely reduce stroke risk. The goal is to develop better prevention …
Matched conditions: SICKLE CELL ANEMIA
Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Apr 03, 2026 14:43 UTC
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CRISPR gene therapy patients monitored for years in groundbreaking study
Disease control ENROLLING_BY_INVITATIONThis study tracks the long-term safety and effectiveness of a one-time CRISPR gene therapy called CTX001 in people with sickle cell disease or beta-thalassemia. It follows 160 children and adults who have already received the therapy in earlier studies. The main goal is to monito…
Matched conditions: SICKLE CELL ANEMIA
Phase: PHASE3 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Mindfulness therapy trial aims to ease sleepless nights for sickle cell patients
Symptom relief TerminatedThis small, remote pilot study is testing whether a type of counseling called Acceptance and Commitment Therapy (ACT) can help adults with sickle cell disease who have trouble sleeping. Participants will have weekly video coaching sessions for 8 weeks and wear a wrist device to t…
Matched conditions: SICKLE CELL ANEMIA
Phase: NA • Sponsor: National Cancer Institute (NCI) • Aim: Symptom relief
Last updated Mar 09, 2026 14:23 UTC
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Scientists probe inner workings of sickle cell drug
Knowledge-focused OngoingThis study aims to understand how the drug mitapivat works in people with sickle cell disease. It involves 6 participants who are already in a larger clinical trial testing the drug. Researchers will take extra blood samples and use a non-invasive skin test to measure oxygen and …
Matched conditions: SICKLE CELL ANEMIA
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC