SEVERE APLASTIC ANEMIA
Clinical trials for SEVERE APLASTIC ANEMIA explained in plain language.
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Breakthrough trial: can a bone marrow transplant beat immune therapy for kids with rare blood disease?
⭐️ CURE ⭐️ OngoingThis study tests whether a bone marrow transplant from an unrelated donor works better than standard immune-suppressing drugs as the first treatment for children and young adults with severe aplastic anemia, a rare condition where the body stops making enough blood cells. About 5…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE3 • Sponsor: Boston Children's Hospital • Aim: ⭐️ CURE ⭐️
Last updated May 26, 2026 07:08 UTC
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New drug combo shows promise for rare blood disorder
Disease control OngoingThis study tests whether adding eltrombopag to standard immune-suppressing drugs helps people with severe aplastic anemia, a rare condition where the immune system attacks bone marrow. About 207 people aged 2 and older with untreated disease will take eltrombopag for up to 6 mont…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE1, PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated May 26, 2026 07:10 UTC
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New drug combo aims to tame stem cell Transplant's worst side effect
Disease control OngoingThis study tests whether adding a drug called cyclophosphamide after a stem cell transplant can reduce the risk of graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. The trial includes 35 adults with various blood cancers who are…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE1, PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 26, 2026 07:00 UTC
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New stem cell combo may boost bone marrow transplant success
Disease control ENROLLING_BY_INVITATIONThis study tests whether adding specially grown umbilical cord stem cells to a standard bone marrow transplant can improve outcomes for people with severe aplastic anemia, a serious condition where the bone marrow stops making enough blood cells. About 40 participants aged 6 to 6…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE1, PHASE2 • Sponsor: Chinese PLA General Hospital • Aim: Disease control
Last updated May 26, 2026 06:58 UTC
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New drug may keep aplastic anemia from returning after standard treatment ends
Disease control OngoingThis study tests whether the drug sirolimus can prevent severe aplastic anemia from coming back after patients stop taking cyclosporine. About 84 people aged 2 and older who have responded to initial treatment will take sirolimus daily for 3 months or receive no extra drug. Resea…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: PHASE2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated May 26, 2026 06:50 UTC
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New transplant technique aims to cut deadly immune reaction in half-matched donors
Disease control OngoingThis study tests a stem cell transplant method that filters out certain immune cells (TCRαβ+ and CD19+) from a half-matched family donor's blood. The goal is to lower the risk of graft-versus-host disease, a serious complication, and allow patients to avoid long-term immune-suppr…
Matched conditions: SEVERE APLASTIC ANEMIA
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 22, 2026 14:02 UTC