SCHIZOPHRENIA AND RELATED DISORDERS
Clinical trials for SCHIZOPHRENIA AND RELATED DISORDERS explained in plain language.
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Could a stronger drug combo early on turn the tide for tough mental health cases?
Disease control Recruiting nowThis study looks at whether giving a more intensive medication plan earlier can help people with schizophrenia, major depression, or bipolar depression who didn't get better with their first treatment. About 1,250 adults will be randomly assigned to either the usual next-step tre…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE3 • Sponsor: Dr. Inge Winter • Aim: Disease control
Last updated May 26, 2026 06:06 UTC
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Could a faster switch to stronger meds change schizophrenia care?
Disease control Recruiting nowThis study tests whether giving a more intensive treatment plan earlier can help people with schizophrenia whose first medication failed. About 418 adults will receive either the intensified treatment or usual care for six weeks. The goal is to see if this approach reduces sympto…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE4 • Sponsor: Dr. Inge Winter • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Could skipping a day of antipsychotics reduce side effects without worsening symptoms?
Disease control Recruiting nowThis study looks at whether taking antipsychotic medication every other day is just as effective as taking it daily for people with schizophrenia. The goal is to see if the extended dosing schedule can reduce side effects while keeping symptoms under control. About 120 adults wil…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE4 • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Magnetic brain zaps aim to lift depression in schizophrenia
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce depression, negative symptoms, and improve thinking in people with schizophrenia. About 180 adults with schizophrenia or schizoaffective disor…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Symptom relief
Last updated May 26, 2026 06:04 UTC
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Can short bursts of exercise beat standard workouts for mental health?
Symptom relief Recruiting nowThis study tests whether brief high-intensity exercise is better than standard high-intensity training for people with schizophrenia or bipolar disorder. Fifty participants will follow one of the two programs for 26 weeks. Researchers will track how many stick with the program an…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: Haukeland University Hospital • Aim: Symptom relief
Last updated May 26, 2026 05:50 UTC
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Can an antioxidant boost brain power in schizophrenia?
Symptom relief Recruiting nowThis study tests whether MitoQ, an antioxidant supplement, can improve thinking and memory in people with early schizophrenia who have signs of mitochondrial problems. Researchers will give MitoQ or a placebo to 50 eligible participants for 12 weeks, alongside their usual medicat…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: PHASE2, PHASE3 • Sponsor: Mclean Hospital • Aim: Symptom relief
Last updated May 26, 2026 05:49 UTC
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Can magnetic pulses lift depression in schizophrenia?
Symptom relief Recruiting nowThis study is testing whether a non-invasive brain stimulation technique called rTMS can improve depressive symptoms in people with schizophrenia. Researchers will use MRI and EEG to measure changes in brain activity. The study aims to enroll 120 adults aged 18-60 who have both s…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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Molding minds: clay therapy may boost daily life for schizophrenia patients
Symptom relief Recruiting nowThis study explores whether clay therapy, a type of art therapy, can improve daily functioning and social performance in people with schizophrenia who are already on medication. Researchers will measure changes in skills like self-care and social interaction. The goal is to see i…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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30-Minute phone app could help At-Risk students sleep better and fight stigma
Symptom relief Recruiting nowThis study tests a 30-minute smartphone app designed to improve sleep and reduce mental health stigma in college students who may be at risk for psychosis. About 115 students with poor sleep and early warning signs will be split into two groups: one gets the app right away, the o…
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated May 19, 2026 11:48 UTC
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Loneliness may speed aging in schizophrenia, study suggests
Knowledge-focused Recruiting nowThis study looks at whether social isolation contributes to the early health problems seen in people with schizophrenia, who often die 10-20 years earlier than others. Researchers will follow 650 participants (500 with schizophrenia and 150 siblings) aged 40-70, tracking medical …
Matched conditions: SCHIZOPHRENIA AND RELATED DISORDERS
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC