SCHIZOPHRENIA

This study tested a 6-month dental health education program for people with schizophrenia. The goal was to see if the program could improve oral hygiene and quality of life compared to standard care. The study was terminated early, so results are limited.

This study tested whether combining a long-acting injectable antipsychotic with cognitive and functional skills training helps people with early schizophrenia achieve symptom remission and better daily functioning. Only one person enrolled before the study was stopped early. The …

This study looked at the long-term safety of the drug iclepertin in adults with schizophrenia who had already completed earlier trials. Participants took iclepertin once a day for one year, along with their usual schizophrenia medication. The study was terminated early, but the g…

This study tested the drug cariprazine (Vraylar) for adults with schizophrenia in Japan and Taiwan. About 250 people were planned, but only 34 enrolled before the study was stopped early. Participants took either cariprazine or a placebo for 6 weeks, then could continue on caripr…

This study aimed to see if a retinal (eye) biomarker could predict how well people with early schizophrenia respond to sodium nitroprusside, an anti-inflammatory drug. It planned to enroll people diagnosed within the last 5 years, but was terminated early after only 1 participant…

This study tested a smartphone-based program to help veterans with serious mental illness (like PTSD, bipolar disorder, or schizophrenia) who struggle to recognize their own emotions—a condition called alexithymia. The goal was to see if improving emotion awareness could reduce s…

This study aimed to understand what helps or gets in the way of using Horyzons, a digital platform with therapy and social features, in clinics for young people with early psychosis. Researchers recruited providers and clients from five clinics in North Carolina and gathered feed…

This study looked at heart disease risk in 48 adults with schizophrenia, schizoaffective disorder, or bipolar disorder who were taking antipsychotic medications. Researchers measured cholesterol levels and heart electrical activity to understand how these drugs might affect the h…

This study looked at whether oxytocin, a natural brain chemical that helps with social bonding, could improve social functioning in veterans with schizophrenia. Researchers planned to use brain scans to see how oxytocin affects the brain and predict who might benefit. The study w…

This study looked at how a non-invasive brain stimulation technique called deep rTMS affects smoking in people with schizophrenia. Researchers used brain scans to measure changes in brain connections and smoking behavior. The study was terminated early but aimed to understand how…