RECURRENT ACUTE MYELOID LEUKEMIA
Clinical trials for RECURRENT ACUTE MYELOID LEUKEMIA explained in plain language.
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New drug combo shows promise for tough leukemia
Disease control CompletedThis early-phase study tested a combination of two drugs, pevonedistat and decitabine, in 12 people with high-risk acute myeloid leukemia (AML). The goal was to find the safest dose and see how well the drugs work together to stop cancer cell growth. Participants had AML that was…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 08:43 UTC
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New combo therapy shows promise for leukemia relapse after transplant
Disease control CompletedThis study tested a drug called guadecitabine combined with donor white blood cell infusions in 55 adults whose leukemia or MDS came back after a stem cell transplant. The goal was to see if the drug could help the donor cells fight the cancer more effectively. The treatment aims…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:42 UTC
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Immune cell therapy shows promise for tough leukemia cases
Disease control CompletedThis early-stage trial tested the safety of using donor natural killer (NK) cells to treat acute myeloid leukemia (AML) that had returned or not responded to standard treatments. Nineteen patients received these immune cells to see if they could help fight the cancer without caus…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: Sumithira Vasu • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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Immunotherapy combo shows promise for Post-Transplant blood cancers
Disease control CompletedThis early-phase study tested two immunotherapy drugs, nivolumab and ipilimumab, in 29 people whose acute myeloid leukemia or myelodysplastic syndrome came back or didn't respond after a donor stem cell transplant. The goal was to find the safest dose and see if the combination c…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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New drug combo targets Hard-to-Treat leukemia
Disease control CompletedThis early-stage trial tested a combination of two targeted drugs, enasidenib and cobimetinib, in 3 adults with a specific genetic form of acute myeloid leukemia (AML) that had returned or not responded to prior treatment. The main goals were to find the safest dose and identify …
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 08:35 UTC
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New hope for kids with relapsed leukemia? early trial tests powerful drug mix
Disease control CompletedThis early-phase study tested a combination of two chemotherapy drugs (CPX-351) and a targeted antibody (gemtuzumab ozogamicin) in children whose acute myeloid leukemia (AML) had come back or stopped responding to treatment. The goal was to find the safest dose and see how well t…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:28 UTC