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New drug combo shows promise for tough leukemia

NCT ID NCT03009240

First seen Apr 23, 2026 · Last updated May 01, 2026 · Updated 1 time

Summary

This early-stage study tested two drugs, pevonedistat and decitabine, together in 12 people with high-risk acute myeloid leukemia (AML). The main goal was to find the safest dose and understand side effects. The drugs work by blocking enzymes that cancer cells need to grow. This study did not aim to cure the disease, but to control it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.