RECURRENT ACUTE MYELOID LEUKEMIA
Clinical trials for RECURRENT ACUTE MYELOID LEUKEMIA explained in plain language.
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Experimental Triple-Drug combo for tough leukemia tested, but study stopped early
Disease control TerminatedThis study tested a combination of three drugs—magrolimab, azacitidine, and venetoclax—in adults with acute myeloid leukemia (AML) that had come back or not responded to prior treatment. The goal was to find the best dose and see how well the drugs worked together to control the …
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:49 UTC
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New drug cocktail targets tough leukemia in patients with RUNX1 mutation
Disease control TerminatedThis study tested a combination of two drugs, omacetaxine and venetoclax, in 24 adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that had returned or not responded to treatment. All participants had a specific genetic change called RUNX1. The goal was to…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Leukemia relapse drug combo study stopped early after enrolling just one person
Disease control TerminatedThis study tested a combination of two drugs (DEC-C and venetoclax) for people whose acute myeloid leukemia (AML) returned after a donor stem cell transplant. The goal was to see if the drugs could kill cancer cells and bring about remission. However, the study was stopped early …
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: Sanjay Mohan • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Experimental combo for tough leukemia shows early promise but trial stopped short
Disease control TerminatedThis early-phase study tested two chemotherapy drugs, pevonedistat and belinostat, together in 18 adults with acute myeloid leukemia or myelodysplastic syndrome that returned or didn't respond to prior therapy. The main goal was to find the safest dose and check for side effects.…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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Promising combo for tough leukemias hits roadblock: trial ends early
Disease control TerminatedThis study tested a combination of two drugs, venetoclax and decitabine, in 235 people with certain blood cancers (like acute myeloid leukemia and high-risk myelodysplastic syndrome) that either came back or didn't respond to prior treatment, or in older adults who couldn't handl…
Matched conditions: RECURRENT ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 18, 2026 12:00 UTC