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New drug cocktail shows promise for tough leukemia

NCT ID NCT04188405

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 21 times

Summary

This study tests a combination of three drugs (decitabine, venetoclax, and ponatinib) in 20 people with a rare, aggressive leukemia called Philadelphia chromosome-positive acute myeloid leukemia or chronic myelogenous leukemia in blast phase. The goal is to see if the drugs can shrink or control the cancer. Participants take the drugs by mouth or IV, and the study tracks how many achieve remission after two treatment cycles.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.