RECTAL NEOPLASMS
Clinical trials for RECTAL NEOPLASMS explained in plain language.
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Extra stitches after rectal cancer surgery may cut dangerous leaks
Disease control ENROLLING_BY_INVITATIONThis study tests whether adding extra stitches around the surgical connection after removing low rectal cancer can lower the risk of leaks, a serious complication. About 300 adults with low rectal cancer will be randomly assigned to get either standard surgery or surgery with rei…
Matched conditions: RECTAL NEOPLASMS
Phase: NA • Sponsor: Shanghai 10th People's Hospital • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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New combo therapy aims to save rectums from radical surgery
Disease control OngoingThis study tests two radiation approaches (short-course or long-course) followed by chemotherapy to shrink low rectal tumors. The goal is to achieve a complete response so patients can avoid major surgery and keep their rectum. About 66 adults with stage 2-4a rectal cancer will p…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE2 • Sponsor: Pei-Rong Ding • Aim: Disease control
Last updated May 26, 2026 08:15 UTC
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New staple technique aims to cut dangerous leaks in rectal cancer surgery
Disease control ENROLLING_BY_INVITATIONThis study tests a modified stapling technique (MST) against the standard method in 450 adults having minimally invasive rectal cancer surgery. The goal is to see if MST reduces the risk of anastomotic leakage, a serious complication where the bowel connection leaks. Participants…
Matched conditions: RECTAL NEOPLASMS
Phase: NA • Sponsor: Korea University Anam Hospital • Aim: Disease control
Last updated May 26, 2026 08:13 UTC
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Immunotherapy combo shows promise in rectal cancer after standard treatment
Disease control OngoingThis study tests whether adding two immunotherapy drugs (atezolizumab and tiragolumab) after standard chemoradiation can help eliminate tumors in people with locally advanced rectal cancer. About 58 participants will receive either the drug combination or atezolizumab alone befor…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 26, 2026 08:10 UTC
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New radiation technique may help rectal cancer patients keep their rectum
Disease control OngoingThis study tests whether a special type of internal radiation (contact X-ray brachytherapy) is better than standard external radiation at helping people with early-stage rectal cancer avoid surgery. About 148 adults with small, early rectal tumors will receive standard chemoradia…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE3 • Sponsor: Centre Antoine Lacassagne • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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Robotic scalpel takes on rectal tumors with precision
Symptom relief OngoingThis study tests a new robotic surgery method for removing rectal tumors. The goal is to make the surgery safer and more precise by using a single-port robot that gives surgeons better vision and control. Twenty patients with benign or early-stage rectal tumors will be treated, a…
Matched conditions: RECTAL NEOPLASMS
Phase: NA • Sponsor: Jeng-Fu You • Aim: Symptom relief
Last updated May 26, 2026 08:20 UTC
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Could a plant compound ease harsh cancer therapy side effects?
Symptom relief OngoingThis study tests whether adding chlorophyllin, a natural compound, to standard cancer treatment can lower side effects like bowel, bladder, and blood problems in people with advanced rectal cancer. About 76 adults will receive either chlorophyllin or a placebo alongside their usu…
Matched conditions: RECTAL NEOPLASMS
Phase: PHASE2 • Sponsor: Tata Memorial Centre • Aim: Symptom relief
Last updated May 18, 2026 12:07 UTC
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Blood test may catch cancer return sooner, boosting cure chances
Knowledge-focused OngoingThis study compares two ways of monitoring colorectal cancer patients after surgery: standard CT scans versus a new approach that also uses a blood test (ctDNA) to find cancer DNA. The goal is to see if the blood test helps detect cancer recurrence earlier and allows more patient…
Matched conditions: RECTAL NEOPLASMS
Phase: NA • Sponsor: Claus Lindbjerg Andersen • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC