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Immunotherapy combo shows promise in rectal cancer after standard treatment

NCT ID NCT05009069

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This study tests whether adding two immunotherapy drugs (atezolizumab and tiragolumab) after standard chemoradiation can help eliminate tumors in people with locally advanced rectal cancer. About 58 participants will receive either the drug combination or atezolizumab alone before surgery. The main goal is to see if the cancer completely disappears by the time of surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, 100142, China

  • First Hospital of China Medical University

    Shenyang, 110001, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, 310009, China

  • The Sixth Affiliated Hospital of Sun Yat-sen University

    Guangzhou, 510655, China

  • Zhongshan Hospital Fudan University

    Shanghai, 200032, China

Conditions

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