PULPITIS - IRREVERSIBLE
Clinical trials for PULPITIS - IRREVERSIBLE explained in plain language.
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New hope for tooth pain: less invasive therapy matches root canal success
Disease control CompletedThis study tested whether a less invasive treatment called vital pulp therapy (VPT) works as well as standard root canal treatment for people with severe, irreversible tooth pulp inflammation. 43 adults with painful back teeth took part, and after 12 months, both treatments had s…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Universidad Central de Venezuela • Aim: Disease control
Last updated May 26, 2026 12:01 UTC
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Tooth nerve tests put to the test: which one tells the truth?
Diagnosis CompletedThis study looked at how well cold, heat, and electric tests can tell if a tooth's nerve is healthy or damaged. Researchers tested 175 adults who needed root canal treatment and compared the test results with directly looking at the nerve during the procedure. The goal was to fin…
Matched conditions: PULPITIS - IRREVERSIBLE
Sponsor: Istanbul University • Aim: Diagnosis
Last updated May 26, 2026 12:05 UTC
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Pre-Procedure pill slashes root canal pain
Symptom relief CompletedThis study looked at whether taking a single dose of the painkiller diclofenac before a root canal can lower pain after the procedure. 160 adults with tooth pain were split into two groups: one got the painkiller 30 minutes before treatment, the other got none. Those who took the…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: College of Physicians and Surgeons Pakistan • Aim: Symptom relief
Last updated May 26, 2026 12:13 UTC
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Tooth pain showdown: probiotics vs antibiotics after root canal
Symptom relief CompletedThis study tested three different pastes placed inside the tooth after root canal treatment to see which one reduces pain best. 75 adults with severe tooth pain received either probiotics, a double antibiotic paste, or calcium hydroxide. Participants reported their pain levels ov…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Dow University of Health Sciences • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Toothache relief: cold water or steroid rinse after Root-Preserving procedure?
Symptom relief CompletedThis study tested whether rinsing the tooth with cold salt water or a steroid solution (dexamethasone) during a tooth-saving procedure reduces pain afterward. 72 adults with severe, irreversible tooth inflammation in a back tooth were treated. The goal was to find a simple way to…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Cukurova University • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Your genes may decide if your root canal numbing works!
Knowledge-focused CompletedThis study looked at whether a specific gene change (rs6746030) affects how well numbing injections work for root canal treatment. Researchers compared 200 patients with successful numbing to 100 with failed numbing. They collected cheek swabs to check for the gene variant. The g…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Jamia Millia Islamia • Aim: Knowledge-focused
Last updated May 26, 2026 12:07 UTC