Pulp necrosis

This trial tests whether transplanting a patient's own minced pulp tissue into a cleaned root canal can regenerate living dental pulp. Fifty participants aged 7 to 50 with infected or inflamed teeth will receive either standard root canal treatment or the experimental tissue tran…

This trial tests whether cocoa husk, a byproduct of chocolate production, can reduce pain and bacteria after root canal treatment. Researchers will compare three approaches in 36 adults with a dead nerve in a lower molar: standard calcium hydroxide, cocoa husk alone, or a mix of …

This study tests a new heat-resistant calcium silicate-based sealer used during root canals in people with infected tooth roots (apical periodontitis). The sealer is applied with different filling techniques to see if it improves bone healing and reduces pain after treatment. Par…

This study tests whether placing omega-3 fatty acids inside a damaged tooth can help it regrow root length and dentin, compared to the standard method of inducing bleeding. Twenty patients aged 6 to 28 with immature permanent teeth that have died due to injury or decay will be tr…

This study looks at two ways to clean root canals (rotary vs. reciprocating files) and whether rinsing with very cold saline (cryotherapy) reduces pain after the procedure. Sixty adults with infected but painless teeth will be randomly assigned to one of four groups. Patients wil…

This study tests two ways to clean a tooth during a root canal: laser-activated irrigation and passive ultrasonic irrigation. Researchers want to see which method leads to less pain and better quality of life afterward. 90 adults with infected or damaged permanent teeth are takin…

This study tests two medications—Chlorhexidine gel and Nitrofurantoin paste—placed inside the tooth during root canal treatment to see which one reduces pain between visits better. 220 patients with infected teeth will report their pain levels before treatment and again after 24 …

This study measures how hot the inside of a tooth gets when dentists shave off a tiny bit of enamel (a common step before braces). Researchers will test two different tools on 40 teeth from 30 people to see which method causes less heat. Keeping the tooth cool is important becaus…