Laser or ultrasound: which root canal method hurts less?
NCT ID NCT07453134
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two ways to clean a tooth during a root canal: laser-activated irrigation and passive ultrasonic irrigation. Researchers want to see which method leads to less pain and better quality of life afterward. 90 adults with infected or damaged permanent teeth are taking part, and their outcomes will be checked after one year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- root canal irrigation (laser-activated or ultrasonic)
- What this could lead to
- If one method works better, dentists may adopt it to reduce pain and improve recovery after root canals.
- What could go wrong
- This is a small, early-stage study with only 90 people. Results may not apply to everyone, and the differences between methods might be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Nov 2025
- Expected to finish
-
Apr 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All permanent teeth diagnosed with any of the following conditions including irreversible pulpitis (symptomatic and asymptomatic), pulp necrosis, previously initiated therapy with or without apical periodontitis o Patients with age 18-80 * Patients with Thai ethnicity * Patients who could read and communicate in Thai language * Patients with well-controlled medical conditions according to ASA I and II classification Exclusion Criteria: * The tooth with cracks, incomplete root formation, vertical or horizontal root fractures or root resorption * The tooth with periodontal pocket depth of 5 mm or more, degree of mobility of 2 or more * Patients with bone metabolism disease and/or using steroids or bisphosphonates, immunosuppressed, history of radiotherapy, pregnancy o Patients with serious medical conditions that required consultation with a physician before root canal treatment * Patients who refuse to participate or could not answer the questionnaires
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chulalongkorn University
Bangkok, 10330, Thailand
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Other studies related to the condition(s) this trial covers.
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