PSORIASIS (PSO)

This study tests a new injection called HB0017 in 200 adults with moderate to severe plaque psoriasis. The goal is to see how well different doses clear the skin and reduce symptoms. Participants will receive either the study drug or a placebo, and their skin improvement will be …

This study tests whether adding semaglutide (a drug used for diabetes and weight loss) to a standard topical cream can improve psoriasis and reduce inflammation. About 62 adults with plaque psoriasis who are overweight or have type 2 diabetes will receive either semaglutide or a …

This study compares two ways to find psoriatic arthritis (PsA) in people with psoriasis: a questionnaire filled out by the patient versus a physical exam by a dermatologist. About 500 adults with psoriasis will be checked using both methods, then referred to a rheumatologist for …

This pilot study is testing an oral medication called roflumilast in 36 adults with moderate-to-severe plaque psoriasis. Participants will take the pill daily for 12 weeks to see if it reduces skin redness, scaling, and thickness. The goal is to gather early information on safety…

This early-stage study tests the safety of an experimental oral drug, LPX-TI641, in 48 adults with atopic dermatitis (eczema) or psoriasis. Participants take the drug or a placebo daily for 28 days. The main goal is to check for side effects and how the drug moves through the bod…

This study follows 80 adults in Canada with moderate-to-severe psoriasis who are starting the drug tildrakizumab as part of their normal care. Researchers will track changes in quality of life and skin clearance over 52 weeks, focusing on people with darker skin types (Fitzpatric…

This early-phase study tests whether adding daily probiotics to standard methotrexate treatment can improve psoriasis symptoms and gut health in newly diagnosed adults. 24 participants will take either probiotics plus methotrexate or methotrexate alone for 4 months. Researchers w…