New study tracks psoriasis Drug's Real-World impact on diverse skin types
NCT ID NCT07370766
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
This study follows 80 adults in Canada with moderate-to-severe psoriasis who are starting the drug tildrakizumab. Researchers want to see how the treatment affects quality of life and skin clearing over one year, especially in people with darker skin tones (Fitzpatrick type III and above). The goal is to understand how well the drug works in real-world settings and to make sure treatment benefits everyone.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with moderate-to-severe psoriasis (PsO) planning to initiate treatment with tildrakizumab and meet Fitzpatrick scale skin type III or above. Patients that are either naïve to PsO treatment with a biologic or those who have previously been exposed to a biologic PsO treatment will be eligible for the study.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adults aged 18 years or older. 2. Diagnosis of moderate-to-severe chronic plaque-type PsO with Fitzpatrick scale type III or above (BSA \>/=3%). 3. Candidate for phototherapy and/or systemic therapy. 4. Planning to initiate tildrakizumab as part of routine clinical care through the ILUMYA SUPPORT® Program for the treatment of plaque PsO but has not yet received their first dose. a. Decision to treat with tildrakizumab must be made independently of and prior to study recruitment. 5. Must be able to read, understand, and communicate in English. 6. Must be willing to participate in the study and capable to provide informed consent 7. Able to comply with all study procedures and attend all study visits Exclusion Criteria: 1. Known hypersensitivity to tildrakizumab, its excipients, or components of the container, as outlined in the Product Monograph. 2. Concurrently taking any oral medication for treatment of PsO (e.g. methotrexate, cyclosporin, acitretin) 3. Diagnosis of only palmoplantar psoriasis 4. Concurrent medical condition or significant comorbidities that, in the investigator's opinion, would prevent participation in the study or interfere with study assessments 5. Women of childbearing potential who are pregnant, planning to become pregnant, or breastfeeding. 6. Prior (within 30 days) or actively participating in other interventional clinical trial(s). 7. Unable or unwilling to comply with study procedures including completing questionnaire. 8. Any other condition that, in the opinion of the investigator, could create a hazard to the participant's safety, endanger the study procedures, or interfere with the interpretation of study results
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
7 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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Benchmark Dermatology
RECRUITINGBurlington, Ontario, L7L 3E5, Canada
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Elevate Dermatology
RECRUITINGPickering, Ontario, Canada
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Factor Dermatology
RECRUITINGOttawa, Ontario, K2A 3Z3, Canada
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Locke Dermatology
RECRUITINGHamilton, Ontario, L8P 4B4, Canada
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Panorama Dermatology Clinic
RECRUITINGKanata, Ontario, K2T 0N7, Canada
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Saskatoon Dermatology Centre
RECRUITINGSaskatoon, Saskatchewan, S7T0G3, Canada
Contact Email: •••••@•••••
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Vital Medical Centre
RECRUITINGOttawa, Ontario, Canada
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